134936-26-8

Basic information

• Product Name: ethyl (R/S)-2--3,3-diethoxypropionate
• Synonyms: ethyl (R/S)-2--3,3-diethoxypropionate
• CAS NO: 134936-26-8
• Molecular Weight: 353.415
• Mol File: 134936-26-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (R/S)-2--3,3-diethoxypropionate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (R/S)-2--3,3-diethoxypropionate(134936-26-8)
• EPA Substance Registry System: ethyl (R/S)-2--3,3-diethoxypropionate(134936-26-8)

Safety Data

• Hazardous Substances Data: 134936-26-8(Hazardous Substances Data)

Upstream product

• 134936-23-5 ethyl (R/S)-2-(dibenzylamino)-3,3-diethoxypropionate 
• 134936-21-3 ethyl (R/S)-2-(dibenzylamino)-3-hydroxy-2-propenoate 
• 134936-24-6 ethyl (R/S)-2-<(benzyloxyethyl)amino>-3,3-diethoxypropionate 
• 61040-21-9 ethyl 2-amino-3,3-diethoxypropanoate 
• 134936-25-7 ethyl (R/S)-2--3,3-diethoxypropionate 

Downstream Products

• 134936-27-9 ethyl 4-benzoyl-5,6-dihydro-1,4-oxazine-3-carboxylate 
• 134936-22-4 ethyl (2R/S,3R/S)-4-benzoyl-2-ethoxymorpholine-3-carboxylate 

Relevant articles and documents

Synthesis of serine analogues to be used as modified phospho acceptor sites in substrates of protein kinase C

Serine and threonine analogues (compounds 2-6) are readily accessible by reaction of the anion of N,N-dibenzylglycine ethyl ester (1) with an appropriate carbonyl compound.These analogues will be incorporated into Protein Kinase C (PKC) substrates.The serine aldehyde derivative 7 was used for the preparation of the corresponding diethyl acetal 9.This compound was the starting material in the synthesis of the suicide precursor 8, featuring a reductive amination leading to 12 and a Lewis-acid-catalysed cyclization giving 8.