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Glycerol phenylbutyrate, also known as Tri(4-phenylbutyryl)glycerol, is a pharmaceutical compound that is currently under development. It is characterized by its unique structure, which consists of three phenylbutyryl chains attached to a glycerol backbone. This structure endows Glycerol phenylbutyrate with specific properties that make it a promising candidate for medical applications.

611168-24-2

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611168-24-2 Usage

Uses

Used in Urea Cycle Disorders Treatment:
Glycerol phenylbutyrate is used as a therapeutic agent for the treatment of urea cycle disorders (UCDs). UCDs are a group of inherited metabolic disorders characterized by the inability of the body to effectively eliminate ammonia, a toxic byproduct of protein metabolism. The accumulation of ammonia in the body can lead to severe neurological damage and even death.
Glycerol phenylbutyrate works by preventing the harmful buildup of ammonia in the body. It achieves this by modulating the activity of enzymes involved in the urea cycle, thereby promoting the conversion of ammonia into urea, which can be safely excreted through urine. This helps to maintain a healthy balance of ammonia levels in the body and prevent the onset of life-threatening complications associated with UCDs.

Check Digit Verification of cas no

The CAS Registry Mumber 611168-24-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,1,1,6 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 611168-24:
(8*6)+(7*1)+(6*1)+(5*1)+(4*6)+(3*8)+(2*2)+(1*4)=122
122 % 10 = 2
So 611168-24-2 is a valid CAS Registry Number.

611168-24-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-bis(4-phenylbutanoyloxy)propyl 4-phenylbutanoate

1.2 Other means of identification

Product number -
Other names glycerol phenylbutyrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:611168-24-2 SDS

611168-24-2Downstream Products

611168-24-2Relevant academic research and scientific papers

Palladium-Catalyzed Direct C-H Arylation of 3-Butenoic Acid Derivatives

Yang, Shan,Liu, Lingling,Zhou, Zheng,Huang, Zhibin,Zhao, Yingsheng

, p. 296 - 299 (2021/01/13)

We report herein a direct method to synthesize 4-aryl-3-butenoic acid through a carboxylic-acid-directed oxidative Heck reaction. The various 4-aryl-3-butenoic acids are easily prepared in moderate to good yields. In view of the promising bioactivity of 4-phenyl-3-butenoic acid previously reported, its derivatives reported here may be bioactive.

AN IMPROVED PROCESS FOR THE PREPARATION OF 1,2,3-PROPANETRIYL TRIS(4-PHENYLBUTANOATE)

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Paragraph 6; 10-12, (2020/05/15)

The present invention relates to an improved process for the preparation of 1,2,3-Propanetriyl tris (4-phenylbutanoate) compound of formula-1, comprising 4-phenyl butyric acid compound of formula-2 with glycerol to provide 1,2,3-Propanetriyl tris (4-phenylbutanoate) compound of formula-1. Further, the present invention relates to process for the purification of 1,2,3-Propanetriyl tris (4-phenyl butanoate) compound of formula-1.

PROCESS FOR THE PREPARATION OF GLYCEROL PHENYLBUTYRATE

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Page/Page column 5, (2015/05/19)

The present invention relates to the process for the preparation of glycerol phenylbutyrate (I) by reacting phenylbutyryl chloride (II) with glycerol (III) in presence of organic base in C1-C5 chlorinated solvent. Glycerol phenylbuty

Glycerol phenyl butyrate esters

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Paragraph 0058, (2013/07/19)

The present invention refers to Glycerol Phenyl Butyrate Esters, including esters and amides, their stereoisomers, enantiomers, racemates as well as the acids, bases or salts thereof, medicaments comprising them, as well as their use in cancer therapy and other pharmaceutical applications. wherein one of R1, R2 or R3 is

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