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Glycerol phenylbutyrate

Base Information
  • Chemical Name:Glycerol phenylbutyrate
  • CAS No.:611168-24-2
  • Molecular Formula:C33H38O6
  • Molecular Weight:530.661
  • Hs Code.:
  • European Community (EC) Number:801-790-7
  • UNII:ZH6F1VCV7B
  • DSSTox Substance ID:DTXSID40210005
  • Nikkaji Number:J3.173.511D
  • Wikipedia:Glycerol_phenylbutyrate
  • Wikidata:Q15322709
  • NCI Thesaurus Code:C170031
  • RXCUI:1368451
  • Metabolomics Workbench ID:151995
  • ChEMBL ID:CHEMBL2105745
  • Mol file:611168-24-2.mol
Glycerol phenylbutyrate

Synonyms:glycerol phenylbutyrate;HPN 100;HPN-100;HPN100;Ravicti

Suppliers and Price of Glycerol phenylbutyrate
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Tri(4-phenylbutyryl)glycerol
  • 25mg
  • $ 65.00
  • TRC
  • Tri(4-phenylbutyryl)glycerol
  • 100mg
  • $ 260.00
  • ChemScene
  • Glycerolphenylbutyrate 99.81%
  • 100mg
  • $ 180.00
  • ChemScene
  • Glycerolphenylbutyrate 99.81%
  • 50mg
  • $ 100.00
  • ChemScene
  • Glycerolphenylbutyrate 99.81%
  • 10mg
  • $ 50.00
Total 18 raw suppliers
Chemical Property of Glycerol phenylbutyrate
Chemical Property:
  • Boiling Point:621.2±45.0 °C(Predicted) 
  • PSA:78.90000 
  • Density:1.131±0.06 g/cm3(Predicted) 
  • LogP:6.05330 
  • XLogP3:6.7
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:20
  • Exact Mass:530.26683893
  • Heavy Atom Count:39
  • Complexity:648
Purity/Quality:

97% *data from raw suppliers

Tri(4-phenylbutyryl)glycerol *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1=CC=C(C=C1)CCCC(=O)OCC(COC(=O)CCCC2=CC=CC=C2)OC(=O)CCCC3=CC=CC=C3
  • Recent ClinicalTrials:PROFIL Study to Investigate the Effect of GPB on NfL Levels in Patients With Corticobasal Syndrome (CBS)
  • Recent EU Clinical Trials:A Randomised, Controlled, Open-Label Parallel Arm Study of the Safety, Pharmacokinetics and Ammonia Control of RAVICTI? (Glycerol Phenylbutyrate [GPB]) Oral Liquid and Sodium Phenylbutyrate (NaPBA) in Phenylbutyrate Treatment Na?ve Patients with Urea Cycle Disorders (UCDs)
  • Uses Tri(4-phenylbutyryl)glycerol is a drug that is currently under development for treatment of urea cyclic disorders (UCDs). It works by preventing the harmful buildup of ammonia in the body.
Technology Process of Glycerol phenylbutyrate

There total 6 articles about Glycerol phenylbutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With 1-methyl-1H-imidazole; In dichloromethane; at -5 - 5 ℃; for 1.5h;
Guidance literature:
With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 30 ℃; for 5h;
DOI:10.1021/acs.orglett.0c03773
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