611174-86-8

Basic information

• Product Name: (2R,3R,4S)-3-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxy)-1-((S)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-2,4-dimethyl-pentan-1-one
• Synonyms: (2R,3R,4S)-3-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxy)-1-((S)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-2,4-dimethyl-pentan-1-one
• CAS NO: 611174-86-8
• Molecular Weight: 633.992
• Mol File: 611174-86-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R,4S)-3-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxy)-1-((S)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-2,4-dimethyl-pentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4S)-3-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxy)-1-((S)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-2,4-dimethyl-pentan-1-one(611174-86-8)
• EPA Substance Registry System: (2R,3R,4S)-3-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxy)-1-((S)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-2,4-dimethyl-pentan-1-one(611174-86-8)

Safety Data

• Hazardous Substances Data: 611174-86-8(Hazardous Substances Data)

Upstream product

• 102831-92-5 (4S)-4-isopropyl-3-(1-oxopropyl)-1,3-thiazolidine-2-thione 

Downstream Products

• 611174-95-9 (2R,3R,4S)-3-(benzyloxy)-5-(tert-butyldiphenylsilyloxy)-2,4-dimethylpentanal 
• 160488-42-6 (2S,3S,4S)-3-(benzyloxy)-5-(tert-butyldiphenylsilyloxy)-2,4-dimethylpentan-1-ol 

Relevant articles and documents

Synthesis of O-benzyl protected anti aldols through the cross-coupling reaction of dibenzyl acetals with a chiral titanium enolate

Addition of the chiral titanium enolate arising from 1 to dibenzyl acetals gives access to anti-β-benzyloxy-α-methyl carboxylic adducts in good yields and with diastereomeric ratios up to 99:1. These adducts can be easily converted into a plethora of enantiopure protected derivatives.