61122-82-5

Usage

Uses

Used in Medicinal Chemistry:
6-(2-CHLORO-ACETYL)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE is used as a chemical compound in medicinal chemistry for its potential pharmacological properties, such as antiviral, antibacterial, and antifungal activities. The presence of the chloroacetyl group may enhance its reactivity and applicability in the development of new drugs.
Used in Drug Discovery:
In the field of drug discovery, 6-(2-CHLORO-ACETYL)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE is utilized as a starting material or a building block for the synthesis of novel compounds with potential therapeutic effects. Its unique structure and the chloroacetyl group may offer specific advantages in the design and synthesis of new pharmaceutical agents.
Further research is necessary to fully explore the potential uses and properties of 6-(2-chloro-acetyl)-3,4-dihydro-1H-quinolin-2-one, as its applications in different industries may vary based on its chemical and biological characteristics.

InChI:InChI=1/C11H10ClNO2/c12-6-10(14)8-1-3-9-7(5-8)2-4-11(15)13-9/h1,3,5H,2,4,6H2,(H,13,15)

Upstream product

• 553-03-7 3,4-dihydro-2(1H)-quinolone 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 145736-62-5 6-<2-((3,4-dimethoxybenzoyl)oxy)acetyl>-3,4-dihydro-2(1H)-quinolinone 
• 142498-75-7 1-(3,4-dihydro-2-oxo-1H-quinolin-6-yl)-2-[4-(2-phenylethyl)piperidin-1-yl]ethanol 
• 103969-58-0 3,4-dihydro-6-(3,6-dihydro-2-oxo-1,3,4-thiadiazin-5-yl)-2(1H)-quinolinone 
• 127805-91-8 (+/-)6-{2-[4-[Bis(4-fluorophenyl)methyl]-1-piperidyl]-1-hydroxyethyl}-3,4-dihydro-2(1H)-quinolinone 
• 620550-82-5 6-[[4-(3-Fluorophenyl)-4-hydroxy-1-piperidinyl]acetyl]-3,4-dihydroquinolin-2(1H)-one 
• 954370-38-8 (+/-)-6-[2-[4-(3-Fluorophenyl)-4-hydroxy-1-piperidinyl]-1-hydroxyethyl]-3,4-dihydroquinolin-2(1H)-one 
• 120067-60-9 6-[1-hydroxy-1-phenyl-2-(imidazol-1-yl)ethyl]-3,4-dihydrocarbostyril 
• 120067-77-8 6-[1-phenyl-2-(imidazol-1-yl)ethyl]-3,4-dihydrocarbostyril 
• 120067-70-1 6-<1-phenyl-2-(1H-imidazol-1-yl)ethenyl>-3,4-dihydroquinolin-2(1H)-one 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS

Compounds and compositions are presented that inhibit K-ras, and especially mutant K-ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.

COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS

Compounds and compositions are presented that inhibit K-Ras, and especially mutant K-Ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.

HETEROCYCLIC COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF

The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.

NEW BICYCLIC DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITIES

The present invention relates to novel compounds having β2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.

2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

A series of 2-(4-hydroxypiperidino)-1-alkanol derivatives are useful as medicaments for the treatment of traumatic injuries to the brain and spinal cord and neuronal degenerative diseases including senile dementias, in mammals, especially humans.

Heteroaryl piperazine antipsychotic agents

Compounds of the formula STR1 and pharmaceutical compositions comprising them, wherein R1, Z, X, W and Y are as defined below. The compounds are useful in the treatment of psychosis and anxiety.

3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase

A series of 1H-imidazol-1-yl- and 3-pyridyl-substituted 3,4- dihydroquinolin-2(1H)-ones was designed and synthesized as combined inhibitors of thromboxane (TXA2) synthase and cAMP phosphodiesterase (PDE) in human blood platelets. A number of st

4-(1,2-benzisoxazolyl)piperidine antipsychotic agents

Certain 1-substituted 4-(1,2-benzisoxazolyl)piperidine compounds exhibit neuroleptic activity and are useful in the treatment of psychosis and anxiety.

Bicyclic heteroaryl thiazole compounds, cardiotonic compositions including the same, and their uses

Cardiotonic fused aromatic bicyclic ring substituted thiazole compounds and their salts, methods for increasing cardiac contractility in humans and other mammals by the use of said compounds, pharmaceutical compositions including said compounds and methods for compound preparation.

Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors

The invention concerns a method of inhibiting both thromboxane synthetase and cyclic-AMP phosphodiesterase in a mammal having a disease characterized by elevated thromboxane levels or an imbalance of prostacyclin/thromboxane levels with a compound of the