61152-62-3

Basic information

• Product Name: 4-(3,4-Dihydroxyphenyl)-2-butane
• Synonyms: 4-(3,4-Dihydroxyphenyl)-2-butane;4-(3,4-Dihydroxyphenyl)-2-butanone;4-(3,4-Dihydroxyphenyl)butan-2-one
• CAS NO: 61152-62-3
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.20048
• Mol File: 61152-62-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 85.5-86 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4))
• Boiling Point: 220-221 °C(Press: 8 Torr)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9.78±0.10(Predicted)
• CAS DataBase Reference: 4-(3,4-Dihydroxyphenyl)-2-butane(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,4-Dihydroxyphenyl)-2-butane(61152-62-3)
• EPA Substance Registry System: 4-(3,4-Dihydroxyphenyl)-2-butane(61152-62-3)

Safety Data

• Hazardous Substances Data: 61152-62-3(Hazardous Substances Data)

Usage

General Description

4-(3,4-Dihydroxyphenyl)-2-butane is a chemical compound that is also known as L-Dopa. It is an amino acid that is produced naturally by the human body and is also used for various medicinal purposes. Its chemical formula is C9H11NO4. L-Dopa serves as a precursor to dopamine, norepinephrine, and epinephrine, which are neurotransmitters responsible for a number of important brain functions such as mood regulation and motor control. Importantly, it is used as a treatment for Parkinson's disease, a neurological condition characterized by the loss of dopamine-producing cells in the brain. It works by replenishing dopamine levels in the patients' brains, thereby easing their symptoms.

Upstream product

• 5471-51-2 4-(4-hydroxyphenyl)-2-oxobutane 
• 121-33-5 vanillin 
• 1080-12-2 Dehydrozingerone 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 123694-03-1 (E)-4-(3′,4′-dihydroxyphenyl)but-3-en-2-one 
• 122-48-5 4-(4-hydroxy-3-methoxyphenyl)-2-butanone 

Downstream Products

• 79622-76-7 3,4-Dimethoxy-(3'-hydroxybutyl)-benzol 
• 63212-99-7 (4E,6E)-1-(3,4-dihydroxyphenyl)-7-phenylhepta-4,6-dien-3-one 
• 61152-58-7 4-(3',4'-dihydroxyphenyl)-2-butanol 

Relevant articles and documents

Synthesis of Yakuchinone B-Inspired Inhibitors against Islet Amyloid Polypeptide Aggregation

Type 2 diabetes mellitus (T2DM) is associated with pancreatic β-cell dysfunction and insulin resistance. Islet amyloid polypeptide (IAPP) aggregation is found to induce islet β-cell death in T2DM patients. Recently, we demonstrated that yakuchinone B deri

Anchimerically Assisted Selective Cleavage of Acid-Labile Aryl Alkyl Ethers by Aluminum Triiodide and N, N-Dimethylformamide Dimethyl Acetal

Aluminum triiodide is harnessed by N,N-dimethylformamide dimethyl acetal (DMF-DMA) for the selective cleavage of ethers via neighboring group participation. Various acid-labile functional groups, including carboxylate, allyl, tert-butyldimethylsilyl (TBS), and tert-butoxycarbonyl (Boc), suffer the conditions intact. The method offers an efficient approach to cleaving catechol monoalkyl ethers and to uncovering phenols from acetal-type protecting groups such as methoxymethyl (MOM), methoxyethoxymethyl (MEM), and tetrahydropyranyl (THP) chemoselectively.

Synthesis of new biosynthetically important diarylheptanoids and their oxa- and fluoro-analogues by three different strategies

Wittig, aldol and Wittig-Horner reactions have been used to synthesize new diarylheptanoids, which are putative intermediates in phenylphenalenone biosynthesis in plants. The Wittig-Horner approach was most suitable and gave significantly higher yields in comparison with other methods.