6116-91-2Relevant academic research and scientific papers
Efficient synthesis of α-benzylidene-γ-methyl-γ-butyrolactones
Mali, Raghao S.,Babu, Kantipudi N.
, p. 3525 - 3531 (2007/10/03)
A concise synthesis of α-benzylidene-γ-methyl-γ-butyrolactones 5a - g from substituted benzaldehydes is described. Compounds 1a - g on reaction with phosphorane 2, provide the pentenoates 3a - g, which can be hydrolyzed to the acids 4a - g. The latter are cyclized to the corresponding butyrolactones 5a - g in excellent yields. The pentenoates 3a - g, on acid catalyzed cyclization, also provide 5a - g in very high yields.
3aH-Indenes. Part 5. Preparation and Reactions of 3-Methoxy- and 3-Trimethylsiloxy-3a-substituted-3aH-indenes
Gibbard, Howard C.,Moody, Christopher J.,Rees, Charles W.
, p. 723 - 730 (2007/10/02)
Previous work on the synthesis and cycloaddition of 3a-methyl-3aH-indenes (1a) and (1b) has been extended to substituents other than methyl at the ring junction.However, the increased migratory aptitudes of these substituents limits the scope of the 3aH-i
