612040-76-3Relevant academic research and scientific papers
Stereoselective Cyclization Mediated by Samarium(II) Iodide Using Allyl Sulfides and Sulfones as Ketyl Radical Acceptors
Kan, Toshiyuki,Nara, Shinji,Ito, Shinya,Matsuda, Fuyuhiko,Shirahama, Haruhisa
, p. 5111 - 5113 (1994)
This paper describes the new types of completely stereoselective cyclizations induced by samarium(II) iodide using allyl sulfides or sulfones as a ketyl radical acceptor.
Conformational effects on lipase-mediated acylations of 2-substituted cyclohexanols
Tanikaga, Rikuhei,Matsumoto, Yoshimasa,Sakaguchi, Maki,Koyama, Yohei,Ono, Kentaro
, p. 6781 - 6783 (2007/10/03)
Lipase-mediated acetylations of trans- and cis-2-substituted cyclohexanols gave the corresponding (1R)-cyclohexyl acetates and (1S)-cyclohexanols in high yields and ee, but c-4-tert-butyl-c-2-ethenyl-r-1-cyclohexanol was unreactive owing to the steric interaction between the axial OH group and the axial H atoms at the 3- and 5-positions. In the cis-isomer the OH group occupies an equatorial position to bind to the lipase, and less bulky axial alkenyl and alkynyl groups might not so much prevent acetylations than an alkyl group.
