612097-82-2

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 271-63-6 7-Azaindole 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 281658-42-2 3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 612097-74-2 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-piperidine-1-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

7-azaindole heterocyclic compound and preparation method and application thereof

The invention belongs to the technical field of 7-azaindole heterocyclic compounds, and discloses a 7-azaindole heterocyclic compound and a preparation method and application thereof. The structure of the compound is shown as a general formula I, a general formula II, a general formula III or a general formula IV (detailed description). The compound can simultaneously have a good effect of inhibiting central nervous excitation on cell and mouse excitation models, and the compound has relatively low neurotoxicity.

7-AZAINDOLE OR 4,7-DIAZAINDOLE DERIVATIVES AS IKK EPSILON AND TBK1 INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Provided are 7-azaindole or 4,7-diazaindole derivatives as an IKKε (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor. The 7-azaindole or 4,7-diazaindole derivative effectively inhibits IKKε and TBK1, and thus is useful not only as an a

AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS

This invention is directed to new potent and selective antagonists of H1 histamine receptors having the general formula (I) to processes for their preparation; to pharmaceutical compositions comprising them; and to their use in therapy.