61227-36-9

Upstream product

• 700-44-7 6-methoxysalicylaldehyde 
• 100-39-0 benzyl bromide 
• 875110-09-1 2-benzyloxy-6-methoxybenzoic acid benzyl ester 
• 1378776-80-7 C₈H₇O₄^(1-)*Na⁽¹⁺⁾ 
• 3147-64-6 2-hydroxy-6-methoxybenzoic acid 
• 628330-46-1 (2-Benzyloxy-6-methoxyphenyl)methanol 

Downstream Products

• 61227-29-0 1-(2-Benzyloxy-6-methoxyphenyl)prop-2-in-1-ol 
• 167831-46-1 3,5-bis-benzyloxy-4-[(2-benzyloxy-6-methoxy-phenyl)-hydroxy-methyl]-benzoic acid tert-butyl ester 
• 167831-48-3 3,5-bis-benzyloxy-4-(2-benzyloxy-6-methoxy-benzoyl)-benzoic acid 
• 167831-47-2 3,5-bis-benzyloxy-4-(2-benzyloxy-6-methoxy-benzoyl)-benzoic acid tert-butyl ester 
• 905562-60-9 1-benzyloxy-3-methoxy-2-(2-methoxyvinyl)benzene 
• 603-35-0 triphenylphosphine 
• 875110-14-8 3-methoxy-2-(4-methoxybenzyl)phenol 
• 152608-83-8 ethyl 3-(2-hydroxy-6-methoxyphenyl)propionate 
• 1255787-65-5 2-(2-hydroxy-6-methoxy-phenyl)-5,5-dimethyl-3-(4-phenoxy-benzyl)-oxazolidin-4-one 
• 1255787-61-1 2-(2-benzyloxy-6-methoxy-phenyl)-5,5-dimethyl-3-(4-phenoxy-benzyl)-oxazolidin-4-one 
• 1255787-51-9 2-(2-isopropoxy-6-methoxy-phenyl)5,5-dimethyl-3-(4-phenoxybenzyl)-oxazolidin-4-one 
• 1255787-60-0 2-(2-benzyloxy-6-methoxy-phenyl)-5,5-dimethyl-oxazolidin-4-one 
• 1323952-70-0 (E)-6-(benzyloxy)-1-[2-(benzyloxy)-6-methoxyphenyl]hex-1-en-3-one 
• 875110-12-6 (2-Benzyloxy-6-methoxyphenyl)-(4-methoxyphenyl)methanol 

Relevant academic research and scientific papers

NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES

A cyclohexane derivative having the function of reducing a blood sugar level and having preferable properties required of medicines, such as long-lasting drug activity, metabolic stability, and safety; and a medicinal composition for use in the prevention or treatment of diseases attributable to hyperglycemia, such as diabetes, e.g., insulin dependent diabetes mellitus (type 1 diabetes) or noninsulin-dependent diabetes mellitus (type 2 diabetes), complications of diabetes, and obesity. The derivative is a compound represented by the formula (I): (wherein A is -O-, -CH2-, or -NH-; n is an integer selected between 0 and 1; R6 and R7 each independently is hydrogen or C1-6 alkyl; m is an integer selected among 1-3; Q is selected among the following formulae Q1 to Q5; Ar1 is optionally substituted arylene or optionally substituted heteroarylene, provided that the heteroarylene may be bonded to an aromatic carbocycle or aromatic heterocycle to form a fused ring; and Ar2 is optionally substituted aryl or optionally substituted heteroaryl), a prodrug of the compound, or a pharmaceutically acceptable salt of either. Also provided are a medicine, a medicinal composition, or the like each containing the compound.

1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY

A compound represented by the formula (1) wherein ring A is a ring optionally having 1 to 3 substituents; ring B is a 1,2-azole ring which may further have 1 to 3 substituents; Xa, Xb and Xc are the same or different and each is a bond, - O -, - S - and the like; Ya is a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; Yb and Yc are the same or different and each is a bond or a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; ring C is a monocyclic aromatic ring which may further have 1 to 3 substituents; and R represents -OR4 (R4 is hydrogen atom or optionally substituted hydrocarbon group) and the like, or a salt thereof or a prodrug thereof is useful as an agent for the prophylaxis or treatment of diabetes and the like.