61255-82-1 Usage
General Description
1H-Pyrazole-1-propanenitrile, 5-amino-3-methyl-(9CI) is a chemical compound with the molecular formula C6H8N4. It is a derivative of pyrazole and contains a nitrile group and an amino group. 1H-Pyrazole-1-propanenitrile,5-amino-3-methyl-(9CI) is mainly used in the pharmaceutical industry for the synthesis of various organic molecules. It is known for its wide range of biological activities, including anti-tumor, antibacterial, and antifungal properties. Additionally, it has been studied for its potential use in the treatment of various diseases, making it a valuable intermediate in organic synthesis and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 61255-82-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,2,5 and 5 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 61255-82:
(7*6)+(6*1)+(5*2)+(4*5)+(3*5)+(2*8)+(1*2)=111
111 % 10 = 1
So 61255-82-1 is a valid CAS Registry Number.
61255-82-1Relevant articles and documents
The reaction of amino-imidazoles, -pyrazoles and -triazoles with α,β-unsaturated nitriles
Komykhov, Sergey A.,Ostras, Konstantin S.,Kostanyan, Alvard R.,Desenko, Sergey M.,Orlov, Valery D.,Meier, Herbert
, p. 1111 - 1116 (2005)
The reactions of α,β-unsaturated nitriles (1, 9, 12) as bielectrophiles with aminoazoles (2, 4, 6) as binucleophiles were investigated. Acrylonitrile (1) reacts almost exclusively in a chemoselective Michael-type addition yielding the substituted azoles 3, 5 and 7, respectively. Cinnamonitriles 9a,b behave in a similar way, but the free CN group adds a second molecule 4 yielding 10a,b and its cyclocondensation product 11a,b as minor component. The attempted formation of azolopyrimidines is best achieved by the reaction of the benzylidenemalononitriles 12a - f with 2 or 4. The process is chemo- and regioselective. The structure determinations were based on NMR measurements including DEPT, COSY, ROESY, HMQC and HMBC techniques and correct earlier suggestions.
