353-07-1

Basic information

• Product Name: 2-CYANOETHYLHYDRAZINE
• Synonyms: Propanenitrile, 3-hydrazino-;BETA-CYANOETHYLHYDRAZINE;CYANOETHYLHYDRAZINE;3-HYDRAZINOPROPIONITRILE;2-CYANOETHYLHYDRAZINE;2-Cyanoethylhydrazine,90%;2-Cyanoethylhydrazine,98%;2-Cyanoethylhydrazine,95%
• CAS NO: 353-07-1
• Molecular Formula: C₃H₇N₃
• Molecular Weight: 85.11
• EINECS: -0
• Product Categories: pharmacetical;Building Blocks;Chemical Synthesis;Hydrazines;Nitrogen Compounds;Organic Building Blocks
• Mol File: 353-07-1.mol

Chemical Properties

• Boiling Point: 76-79 °C0.5 mm Hg(lit.)
• Flash Point: 228 °F
• Appearance: Clear slightly yellow/Liquid
• Density: 1.045 g/mL at 25 °C
• Vapor Pressure: 0.000815mmHg at 25°C
• Refractive Index: n 20/D 1.4776
• Storage Temp.: 0-6°C
• PKA: 6.47±0.10(Predicted)
• Water Solubility: Soluble in water.
• Sensitive: Hygroscopic
• BRN: 773834
• CAS DataBase Reference: 2-CYANOETHYLHYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANOETHYLHYDRAZINE(353-07-1)
• EPA Substance Registry System: 2-CYANOETHYLHYDRAZINE(353-07-1)

Safety Data

• Hazard Codes: T
• Statements: 25-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2927 6.1/PG 2
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 353-07-1(Hazardous Substances Data)

Usage

Chemical Properties

clear slightly yellow liquid

InChI:InChI=1/C3H9N3/c4-2-1-3-6-5/h1,3,6H2,5H3/q+2

Upstream product

• 107-13-1 acrylonitrile 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 93332-17-3 N,N'-Dibenzoyl-N'-(2-cyan-ethyl)-hydrazin 
• 5678-77-3 1,1-bis(cyanoethyl)hydrazine 
• 61255-82-1 3-(5-amino-3-methylpyrazol-1-yl)propionitrile 
• 56054-53-6 3-Phenyl-3-ketopropionitiril-3-acetyl-β-cyanoethyl-hydrazon 
• 56174-95-9 (Z)-2-{[(2-Cyano-ethyl)-hydrazono]-phenyl-methyl}-3-(4-dimethylamino-phenyl)-acrylonitrile 
• 53050-41-2 C₂₁H₂₄N₈O₂ 
• 77619-87-5 3-methyl-4-phenyl-5-oxo-4,5,6,7-tetrahydropyrazolo<1,5-a>-pyrimidine 
• 170300-76-2 (2-cyanoethyl)hydrazone of 4-(benzyloxy)benzaldehyde 
• 1225387-04-1 1-(1-(2-cyanoethyl)-3-(2-methoxy-2-oxoethyl)-4-phenyl-1H-pyrazol-5-yl)-2-methoxy-2-oxoethyl benzoate 
• 2361-34-4 3-(3-methyl-5-oxo-2,5-dihydro-pyrazol-1-yl)-propionitrile 
• 30152-40-0 3-[(1-phenyl-ethylidene)-hydrazino]-propionitrile 

Relevant articles and documents

Stable Yellow Imidazolium Compounds

Described herein is a yellow imidazolium chromophore having a structure according to Formula V.

1-HEXYL-1H-PYRAZOLE-4,5-DIAMINE HEMISULFATE, AND ITS USE IN DYEING COMPOSITIONS

1-hexyl-1H-pyrazole-4,5-diamine hemisulfate, as represented in formula (IX-a), and its use in oxidative dyeing composition. This pyrazole salt was found to combine good stability as raw material and good shade intensity with a range of common couplers when formulated in hair dyeing composition.

Telescoping Synthesis of 5-Amino-4-Nitroso-1-Alkyl-1H-Pyrazole Salt

A telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt derivatives of formula (I), the compound (I) itself, and its use as an intermediate in the fabrication of 1-alkyl-4,5-diaminopyrazole salts of general formula (IX). The compounds of formula (IX) can be used as precursor dyes in oxidative hair dye compositions. R is a mono- or poly-substituted or unsubstituted, straight or branched, saturated or mono- or poly-unsaturated, alkyl group. HZ and HZ′ are organic or mineral acids.

TELESCOPING SYNTHESIS OF 5-AMINO-4-NITROSO-1-ALKYL-1H-PYRAZOLE SALTS

A telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt derivatives of formula (I), the compound (I) itself, and its use as an intermediate in the fabrication of 1-alkyl-4,5-diaminopyrazole salts of general formula (IX). The compounds of formula (IX) can be used as precursor dyes in oxidative hair dye compositions. R is a mono- or poly- substituted or unsubstituted, straight or branched, saturated or mono-or poly- unsaturated, alkyl group. HZ and HZ' are organic or mineral acids.

1-Hexzl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions

1-hexyl-1H-pyrazole-4,5-diamine hemisulfate, as represented in formula (IX-a), and its use in oxidative dyeing composition. This pyrazole salt was found to combine good stability as raw material and good shade intensity with a range of common couplers when formulated in hair dyeing composition.

Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides

A series of hydrazonotrifluorosulfonanilide derivatives were synthesized and evaluated for in vitro activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. Some compounds with excellent activity against tick were identified.

PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS

The present invention provides a compound of formula (I) or a salt thereof (in particular, a pharmaceutically acceptable salt thereof): The invention also provides the use of the compounds or salts as inhibitors of phosphodiesterase type IV (PDE4) and/or

PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS

The invention provides a compound of formula (I) or a salt thereof: wherein Ar has the sub-formula (x): and wherein: Q1 is NH or NMe, in which case Q2 is -C(O)-, -S(O)2-, -C(O)NH- or -C(O)NMe-; or Q1 is a bond o

Synthesis of 2-benzyl-2H-pyrazole-3,4-diamine dihydrochloride

This report describes a straightforward, high yield synthesis of a previously inaccessible N-protected diaminopyrazole in five steps starting from acrylonitrile, hydrazine and benzaldehyde.

3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives: Inhibitors of immune complex induced inflammation

3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives were evaluated in the dermal and pleural reverse passive Arthus reactions in the rat. In the pleural test these compounds were effective in reducing exudate volume and accumulation of white blood cells. This pattern of activity was similar to that of hydrocortisone and different from that of indomethacin. The structural requirements for inhibiting the Arthus reactions were studied by systematic chemical modification of 1. These structure-activity relationship studies revealed that nitrogen 1' of the hydrazino group is essential for activity and must be electron rich, whereas chemical modifications of other sites of 1 had only a modest effect on activity.