61266-55-5Relevant articles and documents
Preparation method and application of 2-hydroxymethyloxetane derivative
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, (2018/12/14)
The invention discloses a preparation method and application of a 2-hydroxymethyloxetane derivative. The method comprises the following steps that a compound II and a compound III are used as raw materials; Barbier reaction is performed to obtain a compound IV; olefinic bonds in the compound IV are cyclized and oxidized to obtain a compound V; under the alkaline condition, ring opening is performed to generate a compound VI; after ring closing reaction, a compound VII is obtained; finally, benzyl protecting groups are removed to obtain the 2-hydroxymethyloxetane derivative (the compound I).
CONCERTED VERSUS STEPWISE PROCESSES IN ELIMINATIVE FISSION OF OXACYCLES
Griffiths, Gwerydd,Stirling, Charles J. M.
, p. 89 - 92 (2007/10/02)
2-Phenylsulphonylmethyloxetan (2a) has been synthesised and the kinetics of base-promoted eliminative ring fission have been determined.The results show, by comparison with the behaviour of related substrates studied previously, that (i) the 3-ring,:4-rin
TRANSPOSITION DES OXIRANNES-ETHANOLS PAR L'INTERMEDIAIRE D'ALCOXYETAINS. INFLUENCE DE LA CONFIGURATION DE L'OXIRANNE
Bats, J.-P.,Moulines, J.,Picard, P.,Leclerq, D.
, p. 3051 - 3054 (2007/10/02)
The transposition of oxirane-ethanols, through alkoxytin compounds, into oxetane-2-methanols and/or oxolan-3-ols (tetrahydrofuran-3-ols) is dependent upon the oxirane configuration.Cis configuration is more suitable for the formation of the smallest ring.Steric hindrance is not sufficient enough to explain the results.