612820-08-3

Upstream product

• 612820-04-9 (2S,4R,5S)-4-benzyl-5-cis-propenylpyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 612820-01-6 (2S,4R)-4-benzyl-5-oxopyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 108963-96-8 (S)-1-tert-butoxycarbonyl-5-methoxycarbonyl-pyrrolidin-2-one 
• 100-39-0 benzyl bromide 
• 612820-06-1 (2S,4R,5S)-4-benzyl-1-but-3-enoyl-5-cis-propenylpyrrolidine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of diversely functionalized indolizidinones and related bicyclic lactams using intramolecular Grubbs olefin metathesis and Dieckmann condensation

Bicyclic 1-aza-2-oxo ring systems with versatile functionality were synthesized from the Grubbs olefin metathesis of appropriate olefinic precursors, starting with L-pyroglutamic acid. The carbocyclization products were further functionalized utilizing th