612833-45-1

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
Ethyl 5-iodo-2-methylbenzoate is used as a reagent in organic synthesis for the preparation of various pharmaceuticals and agrochemicals. Its unique structure and properties make it a valuable component in the development of new and effective compounds for these industries.
Used in Fragrance and Flavoring Industries:
Ethyl 5-iodo-2-methylbenzoate is used as a key ingredient in the production of fragrances and flavorings due to its pleasant aroma. It contributes to the creation of scents and tastes in a wide range of consumer products, including perfumes, cosmetics, and food items.
Used in Materials Science:
Ethyl 5-iodo-2-methylbenzoate has applications in the field of materials science, particularly in the development of new polymers and materials with specific properties. Its unique chemical structure allows for the creation of innovative materials with tailored characteristics for various applications.

InChI:InChI=1/C10H11IO2/c1-3-13-10(12)9-6-8(11)5-4-7(9)2/h4-6H,3H2,1-2H3

Upstream product

• 87-24-1 ethyl 2-methylbenzoate 
• 79669-49-1 5-bromo-2-methylbenzoic acid 
• 359629-91-7 ethyl 5-bromo-2-methylbenzoate 

Downstream Products

• 1260242-01-0 (5-iodo-2-methyl-phenyl)-methanol 
• 612833-44-0 3-(2-bromocyclopent-1-enyl)-6-methylbenzoic acid ethyl ester 

Relevant academic research and scientific papers

N-Iodosuccinimide (NIS) in Direct Aromatic Iodination

N-Iodosuccinimide (NIS) in pure trifluoroacetic acid (TFA) offers a time-efficient and general method for the iodination of a wide range of mono- and disubstituted benzenes at room temperature, as demonstrated in this paper. The starting materials were generally converted into mono-iodinated products in less than 16 hours at room temperature, without byproducts. A few deactivated substrates needed addition of sulfuric acid to increase the reaction rate. Another exception was methoxybenzenes that preferentially were iodinated by NIS in acetonitrile with only catalytic amounts of TFA.

4-METHYL-2,3,5,9,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALENES

The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.

4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes

The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.

THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes.