612833-45-1

Basic information

• Product Name: Ethyl 5-iodo-2-methylbenzoate
• Synonyms: Ethyl 5-iodo-2-methylbenzoate;5-iodo-2-methylBenzoic acid ethyl ester
• CAS NO: 612833-45-1
• Molecular Formula: C₁₀H₁₁IO₂
• Molecular Weight: 290.09761
• Product Categories: Acids & Esters;Iodine Compounds
• Mol File: 612833-45-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 305.974°C at 760 mmHg
• Flash Point: 138.849°C
• Appearance: /
• Density: 1.592g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.577
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Ethyl 5-iodo-2-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 5-iodo-2-methylbenzoate(612833-45-1)
• EPA Substance Registry System: Ethyl 5-iodo-2-methylbenzoate(612833-45-1)

Safety Data

• Hazardous Substances Data: 612833-45-1(Hazardous Substances Data)

Usage

General Description

Ethyl 5-iodo-2-methylbenzoate is a chemical compound with the molecular formula C10H11IO2. It is a derivative of benzoic acid and contains an ethyl ester group, a methyl group, and an iodine atom attached to the benzene ring. Ethyl 5-iodo-2-methylbenzoate is commonly used as a reagent in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. It is also used in the production of fragrances and flavorings. Ethyl 5-iodo-2-methylbenzoate is known for its mild, sweet aroma and is used in the manufacturing of perfumes and cosmetics. Additionally, it has applications in the field of materials science, such as in the development of new polymers and materials with specific properties.

InChI:InChI=1/C10H11IO2/c1-3-13-10(12)9-6-8(11)5-4-7(9)2/h4-6H,3H2,1-2H3

Upstream product

• 87-24-1 ethyl 2-methylbenzoate 
• 79669-49-1 5-bromo-2-methylbenzoic acid 
• 359629-91-7 ethyl 5-bromo-2-methylbenzoate 

Downstream Products

• 1260242-01-0 (5-iodo-2-methyl-phenyl)-methanol 
• 612833-44-0 3-(2-bromocyclopent-1-enyl)-6-methylbenzoic acid ethyl ester 

Relevant articles and documents

N-Iodosuccinimide (NIS) in Direct Aromatic Iodination

N-Iodosuccinimide (NIS) in pure trifluoroacetic acid (TFA) offers a time-efficient and general method for the iodination of a wide range of mono- and disubstituted benzenes at room temperature, as demonstrated in this paper. The starting materials were generally converted into mono-iodinated products in less than 16 hours at room temperature, without byproducts. A few deactivated substrates needed addition of sulfuric acid to increase the reaction rate. Another exception was methoxybenzenes that preferentially were iodinated by NIS in acetonitrile with only catalytic amounts of TFA.

4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes

The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.