359629-91-7

Basic information

• Product Name: 5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER
• Synonyms: 5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER;Benzoic acid, 5-broMo-2-Methyl-, ethyl ester
• CAS NO: 359629-91-7
• Molecular Formula: C₁₀H₁₁BrO₂
• Molecular Weight: 243.11
• Product Categories: Aromatic Esters
• Mol File: 359629-91-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 276.0±20.0 °C(Predicted)
• Appearance: /
• Density: 1.378±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER(359629-91-7)
• EPA Substance Registry System: 5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER(359629-91-7)

Safety Data

• Hazardous Substances Data: 359629-91-7(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-methylbenzoic acid ethyl ester is a chemical compound with the molecular formula C10H11BrO2. It is an organic ester that is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes. 5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER is a white to off-white crystalline solid with a melting point of 58-61°C. It is primarily used in the research and development of new products, as well as in the production of fine chemicals. Additionally, it can also be used as a raw material for the manufacturing of other chemical compounds.

Upstream product

• 7335-32-2 ethyl 5-amino-2-methylbenzoate 
• 64-17-5 ethanol 
• 79669-49-1 5-bromo-2-methylbenzoic acid 

Downstream Products

• 950741-84-1 ethyl 5-bromo-2-(bromomethyl)benzoate 
• 612833-45-1 ethyl 5-iodo-2-methylbenzoate 
• 1260242-01-0 (5-iodo-2-methyl-phenyl)-methanol 
• 1333113-38-4 C₂₄H₃₂O₆ 
• 1280217-75-5 C₁₈H₂₁BrO 
• 1318793-79-1 1-deoxy-1-{3-[1-(4-ethoxyphenyl)-1-methylethyl]-4-methylphenyl}-β-D-glucopyranose 
• 1333071-88-7 2,3,4,6-tetra-O-acetyl-1-deoxy-1-{3-[1-(4-ethoxyphenyl)-1-methylethyl]-4-methylphenyl}-β-D-glucopyranose 
• 1262035-46-0 1-(5-bromo-2-methylphenyl)-1-methylethanol 
• 1613147-69-5 ethyl 5-bromo-2-(((2-ethoxy-2-oxoethyl)(methyl)amino)methyl)benzoate 

Relevant articles and documents

Substituted ring compound and its method and use thereof

The invention provides a substituted cyclic compound as well as a use method and application thereof. The compound is a compound as shown in a formula (I) or stereoisomers, stereomers, tautomers, nitric oxides, solvates, metabolites and pharmaceutically acceptable salts or prodrugs of the compound as shown in the formula (I). The invention further provides a medicament composition containing the compound. The compound and the medicament composition are capable of regulating the activity of protein kinase in a biological sample body and are used for protecting, treating or relieving proliferative diseases of patients. The formula (I) is as shown in the specification.

4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes

The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.

Gem-dimethyl-bearing C-glucosides as sodium-glucose co-transporter 2 (SGLT2) inhibitors

Three novel gem-dimethyl C-glucosides were designed as sodium-glucose co-transporter 2 (SGLT2) inhibitors, and their syntheses started from D-glucose and three 2-substituted-5-bromobenzoic acids were achieved via a facile 8-step protocol, with the key step being anhydrous aluminum chloride-catalyzed Friedel-Crafts alkylation of tertiary alcohols and phenetol. These three SGLT2 inhibitors were evaluated in vivo with a mice oral glucose tolerance test (OGTT), and the anti-hyperglycemic activities of all these three compounds were comparable with that of the positive control Dapagliflozin. Copyright