359629-91-7

Usage

Uses

Used in Pharmaceutical Industry:
5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new medicinal compounds and enhancing the therapeutic potential of existing drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER serves as a key intermediate, playing a crucial role in the production of agrochemicals that aid in crop protection and enhancement of agricultural yields.
Used in Dye Industry:
5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER is utilized as a precursor in the dye industry, facilitating the creation of a diverse range of dyes used in various applications, including textiles, plastics, and printing inks.
Used in Research and Development:
This ester is employed in research and development settings, where it is instrumental in the exploration of new product formulations and the advancement of fine chemical production techniques.
Used as a Raw Material in Chemical Compound Manufacturing:
5-BROMO-2-METHYLBENZOIC ACID ETHYL ESTER also functions as a raw material in the manufacturing of other chemical compounds, broadening its applications across various chemical industries.

Upstream product

• 64-17-5 ethanol 
• 79669-49-1 5-bromo-2-methylbenzoic acid 
• 7335-32-2 ethyl 5-amino-2-methylbenzoate 

Downstream Products

• 950741-84-1 ethyl 5-bromo-2-(bromomethyl)benzoate 
• 612833-45-1 ethyl 5-iodo-2-methylbenzoate 
• 1260242-01-0 (5-iodo-2-methyl-phenyl)-methanol 
• 1333113-38-4 C₂₄H₃₂O₆ 
• 1280217-75-5 C₁₈H₂₁BrO 
• 1318793-79-1 1-deoxy-1-{3-[1-(4-ethoxyphenyl)-1-methylethyl]-4-methylphenyl}-β-D-glucopyranose 
• 1333071-88-7 2,3,4,6-tetra-O-acetyl-1-deoxy-1-{3-[1-(4-ethoxyphenyl)-1-methylethyl]-4-methylphenyl}-β-D-glucopyranose 
• 1262035-46-0 1-(5-bromo-2-methylphenyl)-1-methylethanol 
• 165803-91-8 ethyl 2-methyl-5-vinylbenzoate 

Relevant academic research and scientific papers

Substituted ring compound and its method and use thereof

The invention provides a substituted cyclic compound as well as a use method and application thereof. The compound is a compound as shown in a formula (I) or stereoisomers, stereomers, tautomers, nitric oxides, solvates, metabolites and pharmaceutically acceptable salts or prodrugs of the compound as shown in the formula (I). The invention further provides a medicament composition containing the compound. The compound and the medicament composition are capable of regulating the activity of protein kinase in a biological sample body and are used for protecting, treating or relieving proliferative diseases of patients. The formula (I) is as shown in the specification.

4-METHYL-2,3,5,9,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALENES

The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.

4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes

The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.

SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE

The present invention provides novel substituted alkynyl compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

Gem-dimethyl-bearing C-glucosides as sodium-glucose co-transporter 2 (SGLT2) inhibitors

Three novel gem-dimethyl C-glucosides were designed as sodium-glucose co-transporter 2 (SGLT2) inhibitors, and their syntheses started from D-glucose and three 2-substituted-5-bromobenzoic acids were achieved via a facile 8-step protocol, with the key step being anhydrous aluminum chloride-catalyzed Friedel-Crafts alkylation of tertiary alcohols and phenetol. These three SGLT2 inhibitors were evaluated in vivo with a mice oral glucose tolerance test (OGTT), and the anti-hyperglycemic activities of all these three compounds were comparable with that of the positive control Dapagliflozin. Copyright

THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes.

COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES

Compounds of Formula (I) or (II) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes

ISOINDOLINE COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES

Disclosed is a compound of Formula (I) in which W and R1-R6 are defined herein. Also disclosed is a method of treating spinal muscular atrophy, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced directly or indirectly by mutation or frameshift.