61291-89-2

Basic information

• Product Name: Ethyl2-(4-Bromophenyl)-4-methylthiazole-5-carboxylate
• Synonyms: Ethyl2-(4-Bromophenyl)-4-methylthiazole-5-carboxylate
• CAS NO: 61291-89-2
• Molecular Formula: C₁₃H₁₂BrNO₂S
• Molecular Weight: 326.20888
• Mol File: 61291-89-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl2-(4-Bromophenyl)-4-methylthiazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl2-(4-Bromophenyl)-4-methylthiazole-5-carboxylate(61291-89-2)
• EPA Substance Registry System: Ethyl2-(4-Bromophenyl)-4-methylthiazole-5-carboxylate(61291-89-2)

Safety Data

• Hazardous Substances Data: 61291-89-2(Hazardous Substances Data)

Upstream product

• 623-00-7 4-bromobenzenecarbonitrile 
• 26197-93-3 p-bromothiobanzamide 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 

Downstream Products

• 1428354-60-2 5-(2-(4-bromophenyl)-4-methylthiazol-5-yl)-1,3,4-oxadiazol-2(3H)-thione 
• 1428354-75-9 4-allyl-3-(2-(4-bromophenyl)-4-methylthiazol-5-yl)-1H-1,2,4-triazol-5(4H)-thione 
• 1428354-73-7 3-(2-(4-bromophenyl)-4-methylthiazol-5-yl)-4-methyl-1H-1,2,4-triazol-5(4H)-thione 
• 83432-82-0 3-(2-(4-bromophenyl)-4-methylthiazol-5-yl)-4-phenyl-1H-1,2,4-triazol-5(4H)-thione 
• 1428354-70-4 4-allyl-1-(2-(4-bromophenyl)-4-methylthiazol-5-carbonyl)-thiosemicarbazide 
• 1428354-67-9 1-(2-(4-bromophenyl)-4-methylthiazol-5-carbonyl)-4-methylthiosemicarbazide 
• 83432-73-9 1-(2-(4-bromophenyl)-4-methylthiazol-5-carbonyl)-4-phenylthiosemicarbazide 
• 61291-93-8 [2-(4-bromo-phenyl)-4-methyl-thiazol-5-yl]-methanol 

Relevant articles and documents

Design, synthesis, biological evaluation, common feature pharmacophore model and molecular dynamics simulation studies of ethyl 4-(phenoxymethyl)-2-phenylthiazole-5-carboxylate as Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhi

SHP2 is a non-receptor protein tyrosine phosphatase (PTP) encoded by the PTPN11 gene involved in cell death pathway (PD-1/PD-L1) and cell growth and differentiation pathway (MAPK). Moreover, mutations in SHP2 have been implicated in Leopard syndrome (LS),

Identification of protein tyrosine phosphatase 1B (PTP1B) inhibitors through De Novo Evoluton, synthesis, biological evaluation and molecular dynamics simulation

Protein tyrosine phosphatase 1B (PTP1B) is a widely expressed 50 kDa enzyme and the first intracellular PTP to be purified from human placental tissue. It has been proved that protein tyrosine phosphatase 1B played a significant role in the negative regul

2-substitution-4-methyl-5-(4, 5-thiazoline-2-base)-1, 3-thiazole compound, method for preparing same and evaluation of biological activity

The invention belongs to the field of technologies for chemically synthesizing thiazole derivatives and evaluating the biological activity, and relates to a 2-substitution-4-methyl-5-(4, 5-thiazoline-2-base)-1, 3-thiazole compound shown as a formula I, and further provides a method for preparing 2-substitution-4-methyl-5-(4, 5-thiazoline-2-base)-1, 3-thiazole and evaluation of the biological activity for inhibiting the activity of urease and inhibiting the activity of Escherichia coli, Bacillus subtilis and Staphylococcus aureas. The 2-substitution-4-methyl-5-(4, 5-thiazoline-2-base)-1, 3-thiazole compound, the method and the evaluation have the advantages that the 2-substitution-4-methyl-5-(4, 5-thiazoline-2-base)-1, 3-thiazole compound has certain biological activity, and accordingly the 2-substitution-4-methyl-5-(4, 5-thiazoline-2-base)-1, 3-thiazole compound, the method and the evaluation have excellent application prospects in the industries of medicines, pesticides and the like.