613-28-5

Basic information

• Product Name: p-(dipropylamino)benzaldehyde
• Synonyms: p-(dipropylamino)benzaldehyde;4-(N,N-dipropylamino)benzaldehyde;Benzaldehyde, 4-(dipropylamino)-;EINECS 210-334-0;NSC 156559;NSC156559;TBB000513;ZINC01583083
• CAS NO: 613-28-5
• Molecular Formula: C₁₃H₁₉NO
• Molecular Weight: 205.29606
• EINECS: 210-334-0
• Mol File: 613-28-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 328.6°C at 760 mmHg
• Flash Point: 118°C
• Appearance: /
• Density: 1g/cm³
• Vapor Pressure: 0.000188mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: 2-8°C
• PKA: 2.35±0.32(Predicted)
• CAS DataBase Reference: p-(dipropylamino)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: p-(dipropylamino)benzaldehyde(613-28-5)
• EPA Substance Registry System: p-(dipropylamino)benzaldehyde(613-28-5)

Safety Data

• Hazardous Substances Data: 613-28-5(Hazardous Substances Data)

Usage

General Description

p-(dipropylamino)benzaldehyde is a chemical compound with the molecular formula C13H17NO. It is a benzaldehyde derivative that contains a propylamine side chain attached to the para position of the benzene ring. p-(dipropylamino)benzaldehyde is commonly used as a building block in organic synthesis and is known for its role in the production of pharmaceuticals and other biologically active molecules. It has also been studied for its potential use in the development of new materials and as a fluorescent probe in biological imaging. Additionally, p-(dipropylamino)benzaldehyde has been investigated for its pharmacological properties and its potential use as a research tool in neuroscience.

InChI:InChI=1/C13H19NO/c1-3-9-14(10-4-2)13-7-5-12(11-15)6-8-13/h5-8,11H,3-4,9-10H2,1-2H3

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 91935-18-1 4-bromo-N,N-dipropylaniline 
• 2217-07-4 N,N-dipropylaniline 
• 62-53-3 aniline 
• 622-80-0 N-propylaniline 
• 459-57-4 4-fluorobenzaldehyde 
• 142-84-7 di-n-propylamine 
• 100-97-0 hexamethylenetetramine 

Downstream Products

• 1491163-05-3 (E,E)-2,5-bis{2-[4-(dipropylamino)phenyl]ethenyl}-3,6-di(1-naphthyl)pyrazine 
• 1491163-06-4 (E,E)-2,5-bis{2-[4-(dipropylamino)phenyl]ethenyl}-3,6-bis(4-methoxyphenyl)pyrazine 

Relevant articles and documents

3-hydroxy flavone compound and application thereof

The invention belongs to the technical field of biological fluorescence analysis, and particularly relates to a 3-hydroxy flavone compound and an application thereof. The compound is particularly a 4-n,n-dialkylamino-3-hydroxy flavone compound, and when the compound is used as a fluorescent dye, the lipid droplet targeting property is better, and a cytoskeleton is hardly colored. When conjugated structures such as a benzene ring and the like are added to the left side of a molecule of the compound, the emission wavelength of the molecule can be greatly prolonged, and fluorescence crossing of the molecule from yellow to red is realized. The compound can be applied to the aspects of dynamic lipid droplet imaging in cells, lipid droplet growth process imaging, adipose tissue imaging, even simultaneous imaging of intramuscular fat and intermuscular fat in skeletal muscle tissues, and the like, and has important application values in the fields of fluorescent dyes, biological fluorescent labels and the like.

Monocarboxylate transporter 1 inhibitors as potential anticancer agents

Potent monocarboxylate transporter 1 inhibitors (MCT1) have been developed based on α-cyano-4-hydroxycinnamic acid template. Structure-activity relationship studies demonstrate that the introduction of p-N, N-dialkyl/diaryl, and o-methoxy groups into cyanocinnamic acid has maximal MCT1 inhibitory activity. Systemic toxicity studies in healthy ICR mice with few potent MCT1 inhibitors indicate normal body weight gains in treated animals. In vivo tumor growth inhibition studies in colorectal adenocarcinoma (WiDr cell line) in nude mice xenograft models establish that compound 27 exhibits single agent activity in inhibiting the tumor growth.

Relationship between molecular stacking and optical properties of 9,10-bis((4-N,N-dialkylamino)styryl) anthracene crystals: The cooperation of excitonic and dipolar coupling

Five 9,10-bis((4-N,N-dialkylamino)styryl) anthracene derivatives (DSA-C1-DSA-C7) with different length alkyl chains were synthesized. They showed the same color in dilute solutions but different colors in crystals. The absorption, photoluminescence, and fluorescence decay indicate that there exist both excitonic and dipolar coupling in crystals of DSA-C1-DSA-C7. X-ray crystallographic analysis revealed that all the crystals belong to the triclinic space group P1 with one molecule per unit cell and that the molecules in every crystal have the identical orientation. This offers ideal samples to investigate the impact of the molecular stacking on the optical properties of the crystals. For the first time, the cooperation of excitonic and dipolar coupling has been comprehensively studied, and the contribution to the spectral shift from the excitonic and dipolar couplings quantitatively obtained. The experiments of amplified spontaneous emission (ASE) together with measurements of the quantum efficiency further confirmed this interpretation. The results suggest that the excitonic and dipolar couplings between the adjacent molecules are both important and jointly induce the spectral shifts of the crystals.