61310-39-2

Basic information

• Product Name: 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE
• Synonyms: 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE
• CAS NO: 61310-39-2
• Molecular Formula: C9H8N4O
• Molecular Weight: 188.19
• Mol File: 61310-39-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 364.8±52.0 °C(Predicted)
• Appearance: /
• Density: 1.46±0.1 g/cm3(Predicted)
• PKA: 7.93±0.50(Predicted)
• CAS DataBase Reference: 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE(61310-39-2)
• EPA Substance Registry System: 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE(61310-39-2)

Safety Data

• Hazardous Substances Data: 61310-39-2(Hazardous Substances Data)

Usage

General Description

2-(4-Pyridyl)-4-amino-6-hydroxy pyrimidine is a chemical compound with the molecular formula C8H8N4O. It is a pyridine derivative used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE has potential biological activity and is being studied for its potential use in the treatment of various diseases and disorders. 2-(4-Pyridyl)-4-amino-6-hydroxy pyrimidine may have applications in the development of new drugs and therapies due to its molecular structure and properties.

Upstream product

• 6345-27-3 4-amidinopyridine hydrochloride 
• 105-56-6 ethyl 2-cyanoacetate 

Relevant articles and documents

2, 6 BISHETEROARYL-4-AMINOPYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS

4-Aminopyrimidine derivatives of formula (I) FORMULA heteroaryl groups, including pharmaceutically acceptable salts thereof, wherein R1 and R2 are adenosine A2A receptor antagonists useful in the treatment of movement disorders such as Parkinson's disease.

N-[2-(pyridinyl)-4-pyrimidinyl]ureas

Compounds useful as anti-allergic agents are N-R3 -N-R4 -N'-R-N'-(2-Q-5-R1 -6-R2 -4-pyrimidinyl)ureas (I), where Q is 4- or 3- or 2-pyridinyl or 4- or 3- or 2-pyridinyl having one or two lower-alkyl substituents or N-oxide thereof, R is hydrogen or lower-alkyl, R1 is hydrogen, lower-alkyl or cyano, R2 is hydrogen or lower-alkyl, R3 is hydrogen, lower-alkyl or lower-hydroxyalkyl, R4 is hydrogen, lower-alkyl, lower-hydroxyalkyl, lower-alkenyl or lower-cycloalkyl. Said ureas are prepared by reacting 2-Q-4-RNH-5-R1 -6-R2 -pyrimidine (II) with a carbamylating agent selected from an R4 '-isocyanate of the formula R4 'N=C=O to produce N-R4 '-N'-R-N'-(2-Q-5-R1 -6-R2 -4-pyrimidinyl)urea (IA), an N-R3 '-N-R4 '-carbamyl halide of the formula R3 'R4 'NC(=O)-halide to produce N-R3 '-N-R4 'N'-R-N'-(2-Q-5-R1 -6-R2 -4-pyrimidinyl)urea (IB) or 1,1'-carbonyldiimidazole to produce N-(2-Q-5-R1 -6-R2 -4-pyrimidinyl)-N-R-imidazole-1-carboxamide and then reacting said 1-carboxamide with R3 R4 NH to produce I.