613240-02-1

Usage

Uses

Used in Organic Synthesis:
(4-(4-tert-butylbenzyloxy)phenyl)methanol is used as a building block for the production of various pharmaceuticals, agrochemicals, and materials. It is used as a chiral auxiliary in asymmetric synthesis, which is important for the production of enantiomerically pure compounds.
Used in Pharmaceutical Industry:
(4-(4-tert-butylbenzyloxy)phenyl)methanol is used as a key intermediate in the preparation of bioactive compounds. It has potential applications in medicinal chemistry and drug discovery due to its pharmacological properties.
Used in Agrochemical Industry:
(4-(4-tert-butylbenzyloxy)phenyl)methanol is used as a building block for the production of various agrochemicals.
Used in Materials Industry:
(4-(4-tert-butylbenzyloxy)phenyl)methanol is used as a building block for the production of various materials.
Used in Research and Development:
(4-(4-tert-butylbenzyloxy)phenyl)methanol is important in the field of research and development for its versatile and valuable role in the synthesis of a wide range of compounds.

Upstream product

• 623-05-2 (4-hydroxyphenyl)methanol 
• 172931-92-9 4-(4-tert-butylbenzyloxy)benzaldehyde 
• 18880-00-7 1-(bromomethyl)-4-(1,1-dimethylethyl)benzene 

Downstream Products

• 613240-03-2 4-tert-Butyl-1-(4-chloromethyl-phenoxymethyl)-benzene 
• 613240-52-1 {7-[4-(4-tert-Butyl-benzyloxy)-benzylsulfanyl]-indan-4-yloxy}-acetic Acid Methyl Ester 

Relevant academic research and scientific papers

Sophoridine pyrrole, indole derivative and preparation method and application thereof

The invention relates to a sophoridine pyrrole, indole derivative. The invention discloses a chemical structure of the compound and further discloses a preparation method of the compound. In vitro anti-tumor activity researches show that anti-tumor drugs

Design, synthesis, biological evaluation and structure-activity relationship of sophoridine derivatives bearing pyrrole or indole scaffold as potential antitumor agents

Taking sophoridine as a lead compound, 58 sophoridine derivatives were designed, synthesized and evaluated for their antiproliferative activity in the HepG2 cancer cell line. Among the 58 compounds, 33 compounds showed potent antiproliferative activity wi

2,6-DISUBSTITUTED PYRIDINES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS

Disclosed are compounds of formula (I) wherein R1 and R2 are independently selected from hydrogen, halo, CF3, C1-4alkyl and allyl; Y represents (II), (III), (IV) or (V) wherein R3 represents CF3 or C1-4alkyl; and R3a represents CF3 or C1-4alkyl.

Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists

A series of 1,4-benzyloxybenzylsulfanylaryl carboxylic acids were prepared and their activities for PPAR receptor subtypes (α, δ, and γ) with potential indications for the treatment of dyslipidemia were investigated. Analog 13a displayed the greatest binding affinity (IC50 = 10 nM) and selectivity (120-fold) for PPARδ over PPARα. Many of the analogs investigated were found to be highly selective for PPARδ and were dependent on the point of attachment of the substituent. In the 1,4-series, analog 28e was found to be the most potent (IC50 = 1.7 nM) and selective (>1000-fold) compound for PPARδ. None of the compounds tested showed appreciable binding affinity for PPARγ.

Compounds that modulate PPAR activity and methods for their preparation

This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing disipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of supressing appetite and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.