613243-60-0Relevant academic research and scientific papers
Orthogonal Self-Assembly of Low Molecular Weight Hydrogelators and Surfactants
Heeres, Andre,Van Der Pol, Cornelia,Stuart, Marc,Friggeri, Arianna,Feringa, Ben L.,Van Esch, Jan
, p. 14252 - 14253 (2003)
The concurrent self-assembly of new 1,3,5-trisamide-cyclohexane-based low molecular weight hydrogelators and various surfactants in water leads to the formation of self-assembled fibrillar networks with encapsulated micelles. This prototype system present
Remarkable solvent isotope dependence on gelation strength in low molecular weight hydro-gelators
Canrinus, Tjalling R.,Cerpentier, Florian J. R.,Feringa, Ben L.,Browne, Wesley R.
, p. 1719 - 1722 (2017/02/10)
A delicate interplay of anisotropic hydrophobic/hydrophilic, π-π stacking, ionic and hydrogen bond interactions determine the strength of hydrogelators and are considered key factors in efforts to design potent small molecule hydrogelators. Here we show that solvent deuteration and electrolytic strength affect the strength of hydrogels formed from amino acid modified C3-symmetric cyclohexane trisamides profoundly. Gels formed by self-assembly through heating/cooling of solutions or by pH switching show up to a 30 °C increase in their melting temperatures in D2O compared to H2O. The unusually large solvent isotope effect on gel formation and thermal properties indicates that, in contrast to expectations, hydrogen bonding is not the primary determinant of gel strength but instead that hydrophobic interactions between the gelator molecules and the terminal carboxylic acid units are of greater importance. A conclusion that is supported by a similarly large effect of electrolytes on gel strength.
