613261-30-6Relevant academic research and scientific papers
Lipase-catalyzed separation of the enantiomers of 1-substituted-3-arylthio- 2-propanols
Wielechowska, Monika,Plenkiewicz, Jan
, p. 1199 - 1205 (2005)
Optically active (R)- and (S)-1-substituted-3-(arylthio)propan-2-ols have been prepared in the reaction of the appropriate 2-(arylthiomethyl)oxiranes with chloride and azide anions followed by a lipase-catalyzed transesterification. The effects of the enzyme preparation as well as of the reaction conditions have been compared in terms of the enantiomeric excess of the obtained acetate and unreacted alcohol.
High yield regioselective ring opening of epoxides using samarium chloride hexahydrate
Bhaumik, Kankan,Mali, Umesh W.,Akamanchi
, p. 1603 - 1610 (2007/10/03)
Epoxides were converted to the corresponding β-azidohydrins and β-iodohydrins using SmCl3·6H2O/NaN3 in DMF and SmCl3·6H2/NaI in acetonitrile respectively. The reactions were highly regio-selective, ef
