61345-99-1

Upstream product

• 90612-63-8 3-acetoxy-3,4-dimethyl-pent-4-en-2-one 
• 61345-98-0 3-benzoyloxymethyl-4-methyl-pent-4-en-2-one 
• 61345-97-9 3-acetoxymethyl-4-methyl-pent-4-en-2-one 
• 87061-10-7 (oxo-1' ethyl)-3 methylene-4 tetrahydrothiophenedioxyde-1,1 
• 31554-48-0 3-(bromomethyl)-2,5-dihydrothiophene 1,1-dioxide 
• 814-78-8 3-Methyl-3-buten-2-one 
• 35504-34-8 2,3-dimethyl-pent-1-en-4-yn-3-ol 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 87061-09-4 (oxo-1' ethyl)-3 methyl-4 dihydro-2,5 thiophenedioxyde-1,1 
• 61345-91-3 3-hydroxymethyl-4-methyl-pent-4-en-2-one 

Downstream Products

• 92024-34-5 4-methyl-3-methylene-pent-4-en-2-one-(2,4-dinitro-phenylhydrazone) 

Relevant academic research and scientific papers

CONDENSATION DES NITRILES AVEC LES ORGANOZINCIQUES ALLYLIQUES. APPLICATIONS EN SERIE TERPENIQUE

The reaction of 3-bromomethyl-2,5-dihydrothiophen-1,1-dioxide 6 and 2-bromomethyl-1,3-butadiene 7 with nitriles in the presence of the zinc-silver couple leads to a mixture of ketones 8,9, the pyrolysis of which give the ketones 10 and 11, corresponding respectively to acylation of isoprene at its methyl group from 8, and at C-3 from 9.The reaction of bromide 7 with nitriles leads also to the formation of ketones 10 which by acid isomerisation give the ketones 12 corresponding to an acylation at C-1 of isoprene.In the same way the reaction of 2-(1'-methyl-4'-cyclohexenyl)-3-bromo propene 13 with 3,3-dimethyl acrylonitrile give β- atlantone 14 which is isomerised in acidic medium to α-atlantone 15. 10,11-dihydro α and β-atlantone 16, 17 are obtained by the same procedure from 13 and 3-methyl butyronitrile.