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3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE is an organic compound that serves as a reagent in the synthetic preparation of gelsemine, a natural alkaloid with potential therapeutic applications.
Used in Pharmaceutical Industry:
3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE is used as a synthetic reagent for the preparation of gelsemine, which is utilized in the development of treatments for pathological anxiety. Its role in the synthesis process is crucial for producing gelsemine, a compound with potential anxiolytic properties that can help address anxiety disorders.

31554-48-0

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31554-48-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 31554-48-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,5,5 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 31554-48:
(7*3)+(6*1)+(5*5)+(4*5)+(3*4)+(2*4)+(1*8)=100
100 % 10 = 0
So 31554-48-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H7BrO2S/c6-3-5-1-2-9(7,8)4-5/h1H,2-4H2

31554-48-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(bromomethyl)-2,5-dihydrothiophene 1,1-dioxide

1.2 Other means of identification

Product number -
Other names 3-bromomethyl-3-sulfolene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:31554-48-0 SDS

31554-48-0Relevant academic research and scientific papers

Diversity oriented approach to phenylalanine derivatives via the dielsalder reaction involving sulfolene intermediates

Kotha, Sambasivarao,Bandi, Vijayalakshmi

, p. 226 - 237 (2015/03/04)

We report a new synthetic approach to highly functionalized phenylalanine derivatives via sulfolenes as latent diene equivalents. Here, the DielsAlder reaction has been used as a key step to assemble diverse unusual amino acid derivatives.

Construction of [4.3.1]propellanes via molybdenum fischer carbene complexes.

Bertolini, Thomas M,Nguyen, Que Huong,Harvey, Daniel F

, p. 8675 - 8678 (2007/10/03)

Treatment of molybdenum Fischer carbene complexes with 6-methylene-7-octen-1-yne derivatives at 40 degrees C generates substituted tricyclo[4.3.1.0(1,6)]deca-2,4-dienes in good yield. Pentacarbonyl(butylmethoxycarbene)molybdenum(0) afforded the highest cyclization yields (54%), while the analogous chromium carbene complex gave no reaction. The range of dienyne substrates that participate in this reaction is explored and its mechanism is analyzed and discussed.

Pesticidal phosphoryl- and phosphinyl-thioalkyl cyclic sufones

-

, (2008/06/13)

Compounds of the formula: STR1 wherein X is sulfur or oxygen; R1 is lower alkyl; R2 is lower alkyl, lower straight chain alkoxy, lower alkylthio, phenyl or the group --NR3 R4 where R3 and R4 are independently hydrogen or lower alkyl, provided that when X is oxygen, R2 is not phenyl, are pesticidal, exhibiting activity against pests such as plant fungal diseases and, in many cases, insects.

Decomposition and Isomerization of Bridgehead Cis 1,2-Diazenes (Azoalkanes)

Chae, Woo-Ki,Baughman, Sharon A.,Engel, Paul S.,Bruch, Manfred,Oezmeral, Cenan,et al.

, p. 4824 - 4833 (2007/10/02)

Four acyclic cis 1,2-diazenes, azo-1-adamantane (cis-ada), azo-bicyclooctane (cis-), azo-1-bicycloheptane (cis-), and azo-1-bicyclohexane (cis-) have been generated by UV irradiation of the corresponding trans-isomers.These compounds differ greately in stability, cis- easily surviving at 100 deg C and cis-ada not being isolable.Whereas cis- and cis-only isomerize back to trans on heating, the other two compounds undergo competing loss of nitrogen.The observation that the energy of the transition state for isomerization remains at 42 +/- 1 kcal mol-1 regardless of the cis ground state energy is used to argue that thermal isomerization proceeds via semilinearization rather than rotation.A remarkable correlation of cis ground state energy with cis n,?* excitation energy has emerged from this study.

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