61348-46-7

Basic information

• Product Name: (4E)-N-hydroxy-4H-chromen-4-imine
• CAS NO: 61348-46-7
• Molecular Formula: C₉H₇NO₂
• Molecular Weight: 161.1574
• Mol File: 61348-46-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 285.487°C at 760 mmHg
• Flash Point: 126.458°C
• Density: 1.251g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: (4E)-N-hydroxy-4H-chromen-4-imine(CAS DataBase Reference)
• NIST Chemistry Reference: (4E)-N-hydroxy-4H-chromen-4-imine(61348-46-7)
• EPA Substance Registry System: (4E)-N-hydroxy-4H-chromen-4-imine(61348-46-7)

Safety Data

• Hazardous Substances Data: 61348-46-7(Hazardous Substances Data)

Usage

General Description

(4E)-N-hydroxy-4H-chromen-4-imine, also known as 4keto cyromazine, is a chemical compound commonly used as an insect growth regulator. It is a derivative of cyromazine, which is an insecticide used in agriculture to control fly larvae in livestock production and to manage pests in fruits and vegetables. (4E)-N-hydroxy-4H-chromen-4-imine is a potent inhibitor of ecdysone 20-monooxygenase, an enzyme involved in the synthesis of ecdysone, a hormone essential for the growth and development of insects. Its mode of action disrupts the molting and development of insect larvae, ultimately leading to their death. (4E)-N-hydroxy-4H-chromen-4-imine is considered to have low toxicity to mammals and is typically used in combination with other insecticides for effective pest management.

Upstream product

• 66665-81-4 1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime 
• 491-38-3 1-benzopyran-4(4H)-one 
• 67-56-1 methanol 

Relevant articles and documents

REACTION OF CHROMONES WITH HYDROXYLAMINE IN ANHYDROUS METHANOL. A NOVEL ROUTE FOR THE PREPARATION OF CHROMONE OXIMES

The reaction of 4H-1-benzopyran-4-one (chromone, 1) and its substituted derivatives with hydroxylamine in aqueous alcohols gives isoxazoles 5, and 10, as the major products, whereas 1a is transformed mainly into 8a with hydroxylamine hydrochloride in anhydrous methanol; compounds 5a, 9a and 10a can also be isolated, and the formation of 6a and 7a has been detected, as well.Depending on the character of the substituent, substituted chromones 1b-g afforded 7, 8 or 9 as the isolable major product.Based on the present experiments compound 6, produced in an acid-catalyzed methanol addition on 1, is regarded the key intermediate of the formation of chromone oxime

A NEW PATHWAY IN THE REACTIONS OF CHROMONES AND HYDROXYLAMINE IN ANHYDROUS SOLUTIONS

In the nucleophilic reaction of chromone (1) with NH2OH.HCl in anhydrous methanol a new compound 2-methoxychromanone (6) appeared as an intermediate in the formation of chromone oxime (8) and 2-methoxychromanone oxime (7).