61367-41-7

Basic information

• Product Name: trans-4-MethoxycyclohexanaMine HCl
• Synonyms: trans-4-MethoxycyclohexanaMine HCl;trans-4-Methoxy-cyclohexylamine hydrochloride;trans-4-methoxycyclohexanamine hydrochloride
• CAS NO: 61367-41-7
• Molecular Formula: C₇H₁₅NO*ClH
• Molecular Weight: 165.66104
• Mol File: 61367-41-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 174.5°Cat760mmHg
• Flash Point: 53.1°C
• Appearance: /
• Density: 0.94g/cm³
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: trans-4-MethoxycyclohexanaMine HCl(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-MethoxycyclohexanaMine HCl(61367-41-7)
• EPA Substance Registry System: trans-4-MethoxycyclohexanaMine HCl(61367-41-7)

Safety Data

• Hazardous Substances Data: 61367-41-7(Hazardous Substances Data)

Usage

Uses

trans-4-Methoxycyclohexanamine Hydrochloride is used in the synthesis of analogs of N-?(2-?chloroethyl)?-?N''-?(trans-?4-?methylcyclohexyl)?-?N-?nitrosourea as anticancer agents.

Upstream product

• 56239-26-0 (1s,4s)-4-aminocyclohexan-1-ol hydrochloride 
• 167081-25-6 cis-(4-hydroxycyclohexyl)carbamic acid tert-butyl ester 
• 760958-17-6 tert-butyl ((1r,4r)-4-methoxycyclohexyl)carbamate 
• 111300-06-2 trans-tert-butyl 4-hydroxycyclohexylcarbamate 

Downstream Products

• 1214254-88-2 diethyl {[4-(trans-4-methoxycyclohexylamino)-6-pyrrolidin-1-ylpyrimidin-2-yl]methyl}phosphonate 
• 1214254-89-3 2-[(E)-2-(6,7-difluoro-3-methylquinoxalin-2-yl)vinyl]-N-(trans-4-methoxycyclohexyl)-6-pyrrolidin-1-ylpyrimidin-4-amine 
• 1214254-87-1 diethyl {[4-chloro-6-(trans-4-methoxycyclohexylamino)pyrimidin-2-yl]methyl}phosphonate 
• 2222941-37-7 (S)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4S)-4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)-1-(3,4-difluorophenyl)piperidin-2-one 

Relevant articles and documents

Compounds and methods of use

Compounds are provided according to Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X1, X2, X3, X4, Y, A, L1, L2, R1, R2, R5, m and n are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

BENZIMIDAZOLYL-METHYL UREA DERIVATIVES AS ALX RECEPTOR AGONISTS

The present invention relates to benzimidazolyl-methyl urea derivatives of formula (I), wherein n, D, E, R1, R2, R3, R4, R6, R7, R8 and R9 are as defined in the description, their preparation and their use as pharmaceutically active compounds.

BRADYKININ 1 RECEPTOR ANTAGONISTS

The invention encompasses novel compounds and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for treatment of diseases mediated by B1 bradykinin receptor.