613678-08-3

Usage

Uses

Used in Organic Synthesis:
(6-broMopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone is used as a building block in organic synthesis for its ability to contribute to the formation of complex organic molecules. Its unique structural features allow it to be a valuable component in the creation of new compounds with specific properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (6-broMopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone is used as a research compound to explore its potential in drug development. Its reactivity and structural attributes make it a candidate for further investigation into possible therapeutic applications.

Upstream product

• 215950-19-9 1-methyl-piperidine-4-carboxylic acid methoxy-methyl-amide 
• 626-05-1 2,6-Dibromopyridine 
• 103640-16-0 1-methylpiperidine-4-carboxylic acid diethylamide 
• 613678-14-1 (1-methyl-4-piperidyl)pyrrolidin-1-ylmethanone 
• 613678-09-4 N,N,1-trimethylpiperidine-4-carboxamide 

Downstream Products

• 613678-03-8 (6-aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone 

Relevant academic research and scientific papers

Pyridylpiperidine derivative and application thereof

The invention discloses a pyridylpiperidine derivative and application thereof, and particularly relates to a novel pyridylpiperidine derivative and a pharmaceutical composition containing the compound, which can be used for activating a 5-HT1F receptor.

PYRIDINOYLPIPERIDINES AS 5-HT1F AGONISTS

The present invention relates to compounds of formula I:or pharmaceutically acceptable acid addition salts thereof, where;R1 is C1-C6 alkyl, substituted C1-C6 alkyl, C3-C7 cycloalkyl, substituted C3-C7 cycloalkyl, C3-C7 cycloalkyl-C1-C3 alkyl, substituted C3-C7 cycloalkyl-C1-C3 alkyl, phenyl, substituted phenyl, heterocycle, or substituted heterocycle;R2 is hydrogen, C1-C3 alkyl, C3-C6 cycloalkyl-C1-C3 alkyl, or a group of formula II II;R3 is hydrogen or C1-C3 alkyl; R4 is hydrogen, halo, or C1-C3 alkyl;R5 is hydrogen or C1-C3 alkyl; R6 is hydrogen or C1-C6 alkyl; and n is an integer from 1 to 6 inclusively. The compounds of the present invention are useful for activating 5-HT1F receptors, inhibiting neuronal protein extravasation, and for the treatment or prevention of migraine in a mammal. The present invention also relates to a process for the synthesis of intermediates in the synthesis of compounds of Formula I.