215950-19-9

Usage

Uses

Used in Pharmaceutical Industry:
4-Piperidinecarboxamide, N-methoxy-N,1-dimethylis used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs. Its versatile properties make it a valuable component in drug discovery and design processes.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Piperidinecarboxamide, N-methoxy-N,1-dimethylis utilized as a building block in the creation of agrochemicals, playing a crucial role in the development of effective and safe products for agricultural applications.
Used as a Precursor in Organic Synthesis:
4-Piperidinecarboxamide, N-methoxy-N,1-dimethylis also used as a precursor in the synthesis of other organic compounds, highlighting its importance in the broader field of organic chemistry and the creation of a wide range of chemical products.

Upstream product

• 68947-43-3 1-methylpiperidine-4-carboxylic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 288156-86-5 4-[3-(methylamidyl)benzoyl]-1-methylpiperidine 
• 439239-90-4 Lasmiditan 
• 288156-94-5 4-[3-(4-fluorobenzamidyl)benzoyl]-1-methylpiperidine oxalate 
• 288157-02-8 4-[3-(2-iodo-4-fluorobenzamidyl)benzoyl]-1-methylpiperidine hydrochloride 
• 288156-97-8 4-[3-(benzamidyl)benzoyl]-1-methylpiperidine oxalate 
• 288157-01-7 4-[3-(4-hydroxybenzamidyl)benzoyl]-1-methylpiperidine hydrochloride 
• 288156-88-7 4-[3-(methylamidyl)benzoyl]-1-methylpiperidine oxalate 
• 288157-71-1 4-[3-(phenoxyamidyl)benzoyl]-1-methylpiperidine 
• 288156-95-6 4-[3-(fur-2-ylamidyl)benzoyl]-1-methylpiperidine hydrochloride 
• 288157-41-5 4-[3-(2,3,4,5,6-pentafluorobenzamidyl)benzoyl]-1-methylpiperidine 
• 288157-63-1 4-[3-(2,3,4,5-tetrafluorobenzamidyl)benzoyl]-1-methylpiperidine 
• 288157-64-2 4-[3-(3,4,5-trifluorobenzamidyl)benzoyl]-1-methylpiperidine 
• 288157-42-6 4-[3-(2,6-difluorobenzamidyl)benzoyl]-1-methylpiperidine 
• 288157-68-6 4-[3-(cyclohexylureido)benzoyl]-1-methylpiperidine 

Relevant academic research and scientific papers

2,2-DIMETHYL-N-[6-(1-METHYL-PIPERIDIN-4-CARBONYL)-PYRIDIN-2-YL]-PROPIONAMIDE, METHOD FOR PREPARING (6-AMINO-PYRIDIN-2-YL)-(1-METHYL-PIPERIDIN-4-YL)-METHANONE USING SAID COMPOUND, AND USE OF SAID COMPOUND IN THE PREPARATION OF LASMIDITAN

The present invention relates to a new intermediate, (2,2-dimethyl-N-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-propanamide) useful in the synthesis of lasmiditan, to a method for obtaining same, to the use of said intermediate for preparing lasmiditan, to a method for preparing lasmiditan making use of said intermediate, and to a method for preparing an intermediate ((6-amino-pyridin-2-yl)-(1-methyl-piperidin-4-yl)-methanone) from (2,2-dimethyl-N-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-propanamide).

PROCESS FOR PREPARATION OF LASMIDITAN

The present invention relates to a process for the preparation of lasmiditan, a compound of formula I, or pharmaceutically acceptable salts thereof, the process comprising reacting a compound of formula IX with N-methoxymethylamine or salt thereof to obtain a compound of formula VII; reacting the compound of formula VII with a compound of formula XIV to obtain lasmiditan or salts thereof.

5-HT1f agonist

The present invention relates to a compound of formula I and a process for making: or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT1Freceptors and inhibiting neuronal protein extravasation in a mammal.