6137-08-2

Usage

InChI:InChI=1/C9H18O/c1-4-5-6-7-8(2)9(3)10/h8H,4-7H2,1-3H3

Upstream product

• 814-78-8 3-Methyl-3-buten-2-one 
• 693-03-8 n-butyl magnesium bromide 
• 100536-98-9 2-ethoxy-3-methyl-octan-3-ol 
• 27644-49-1 3-methyl-octan-2-ol 
• 29199-35-7 dibutylborinic acid 1-methyl-hept-1-enyl ester 
• 74-88-4 methyl iodide 
• 109-72-8 n-butyllithium 
• 77144-30-0 2,3-dimethyl-2,3-diaza-4-ketohex-5-ene 
• 917-54-4 methyllithium 
• 110-43-0 n-pentyl methyl ketone 
• 88626-90-8 BuMnCl 
• 67-56-1 methanol 
• 111-13-7 hexyl-methyl-ketone 
• 71-41-0 pentan-1-ol 

Relevant academic research and scientific papers

METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL

The present invention relates to: a method for converting a hydroxyl group of an alcohol; and a catalyst which makes the method possible. A method for converting a hydroxyl group of an alcohol according to the present invention is characterized by producing a compound represented by CH(R1)(R2)Nu (wherein R1, R2 and Nu are as defined below) by reacting an alcohol represented by CH(R1)(R2)OH (wherein each of R1 and R2 represents a hydrogen atom, an optionally substituted alkyl group, or the like) and a compound having an active proton, which is represented by H-Nu (wherein Nu represents a group represented by —CHX1-EWG1 or —NR3R4; X1 represents a hydrogen atom or the like; EWG1 represents an electron-withdrawing group; and each of R3 and R4 represents a hydrogen atom, an optionally substituted alkyl group, or the like), with each other in the presence of a complex of a group 7-11 metal of the periodic table and at least one solid base that is selected from the group consisting of layered double hydroxides, composite oxides and calcium hydroxide.

α-Methylation of Ketones with Methanol Catalyzed by Ni/SiO2-Al2O3

α-Methylation of ketones with methanol catalyzed by a cheap and easy to handle Ni/SiO2-Al2O3 was explored. After optimization of the reaction between propiophenone and methanol, the desired product was obtained in 95 % isolated yield. A wide range of ketones was methylated under the optimized conditions (16 examples). This procedure was extended to a three-component cross-benzylation-methylation of acetophenone.

Charge-Directed Conjugate Addition Reactions in the Preparation of Substituted Methyl Ketones

Charge-directed conjugated addition reactions of the tert-butyl esters of α,β-unsaturated acylphosphoranes 2 have been used to prepare a variety of substituted methyl ketones.Substituted ylides 6 are prepared by alkylating ylide anions 4 generated by the addition of nucleophiles to 2 and are converted under acidic conditions to substituted (acylmethylene)phosphoranes 12 which are hydrolyzed to methyl ketones.The utility of these unsaturated acylphosphoranes as methyl vinyl ketone equivalents in conjugate addition-alkylation reactions is demonstrated in a synthesis of the racemic form of the sex pheromone of the California red scale, 14.