6137-26-4

Basic information

• Product Name: 4-DODECANONE
• Synonyms: 4-DODECANONE;N-OCTYL N-PROPYL KETONE;Octyl propyl ketone;dodecan-4-one;4-Dodecanone,99%;4-DODECANONE 99%;Dodecane-4-one
• CAS NO: 6137-26-4
• Molecular Formula: C₁₂H₂₄O
• Molecular Weight: 184.32
• EINECS: 228-116-9
• Mol File: 6137-26-4.mol
• Article Data: 18

Chemical Properties

• Melting Point: 11.5°C
• Boiling Point: 65°C 0,25mm
• Flash Point: 65°C/0.25mm
• Appearance: /
• Density: 0,83 g/cm3
• Vapor Pressure: 1.62E-08mmHg at 25°C
• Refractive Index: 1.4310
• BRN: 1703138
• CAS DataBase Reference: 4-DODECANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-DODECANONE(6137-26-4)
• EPA Substance Registry System: 4-DODECANONE(6137-26-4)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 6137-26-4(Hazardous Substances Data)

Usage

General Description

4-Dodecanone, also known as dodecan-4-one, is an organic compound with the chemical formula CH3(CH2)8C(O)CH3. This colorless, oily liquid with a mild sweetish-almond, aromatic odor is a member of the ketone family, characterized by a carbonyl group (C=O) linked to two other carbon atoms. Less dense than water, it is insoluble in water but soluble in alcohol and ether. 4-Dodecanone is used in the fragrance industry to add a floral note to perfumes and cosmetics, but it can also be used as a solvent or as an intermediate in organic synthesis. Its vapor can cause irritation to eyes, skin, and respiratory system.

InChI:InChI=1/C14H12BrNO2/c1-10-2-7-13(18-10)8-9-14(17)16-12-5-3-11(15)4-6-12/h2-9H,1H3,(H,16,17)/b9-8+

Upstream product

• 629-27-6 1-Iodooctane 
• 17049-49-9 octylmagnesium bromide 
• 764-85-2 Nonanoyl chloride 
• 112-05-0 nonanoic acid 
• 107-92-6 butyric acid 
• 97-94-9 triethyl borane 
• 6117-91-5 (E/Z)-2-buten-1-ol 
• 111-66-0 oct-1-ene 
• 110-22-5 diacetyl peroxide 
• 123-72-8 butyraldehyde 
• 141-75-3 butyryl chloride 
• 18394-00-8 9-octadecanone 
• 123-38-6 propionaldehyde 
• 98441-95-3 (E)-2-dodecen-4-one 

Downstream Products

• 2437-56-1 1-tridecene 
• 68388-21-6 12,13-tetracosanediol 
• 10203-32-4 4-dodecanol 

Relevant articles and documents

Catalytic ketonisation over oxide catalysts. Part IX. Single step synthesis of aliphatic saturated and unsaturated C11 - C 13 ketones from carboxylic acids

Metameric undecan-x-ones (x = 2-6), dodecan-y-ones (y = 2-5), tridecan-z-ones (z = 4-7) and two unsaturated aliphatic ketones were prepared by vapor phase ketonisation of the appropriate monocarboxylic acids in the presence of 20 wt% MnO2/Al2O3 catalyst under flow conditions. The ketones were obtained in yields between 48 and 89% in a multigram scale (80-250 g). Their physical and spectral data have been determined.

Synthesis of aliphatic ketones from allylic alcohols through consecutive isomerization and chelation-assisted hydroacylation by a rhodium catalyst

Abstract: An allylic alcohol, utilized as a precursor for an aliphatic aldehyde, reacted with olefins to afford aliphatic ketones in the presence of RhCl(PPh3)3, 2-amino-4-picoline, aniline, and benzoic acid through a tandem reaction of an isomerization and a chelation-assisted hydroacylation.