6137-76-4Relevant academic research and scientific papers
Efficient chemoselective addition of grignard reagents to carbonyl compounds in 2-methyltetrahydrofuran
Zhong, Weihui,Wu, Yaotiao,Zhang, Xingxian
experimental part, p. 370 - 373 (2009/12/25)
Compared with tetrahydrofuran (THF) as a solvent for the addition reactions between Grignard reagents and carbonyl compounds 2-methyltetrahydrofuran affords the corresponding adducts in higher yields with higher chemoselectivities. Moreover, 2-methyltetrahydrofuran can be readily recycled and reused, which lowers the cost of the process and makes the reaction greener.
A general sultone route to the pamamycin macrodiolides - Total synthesis of pamamycin-621A and pamamycin-635B
Fischer, Petra,Segovia, Ana Belen Garcia,Gruner, Margit,Metz, Peter
, p. 6231 - 6234 (2007/10/03)
(Chemical Equation Presented) Sultones swing again: The first total syntheses of the title antibiotics (see scheme) were achieved by application of sultone methodology. Since the final lactonizations with formation of the ester linkage between C1′ and the
