61375-52-8

Basic information

• Product Name: (2RS,1'SR)-2-(1',4'-dimethylcyclohex-3'-enyl)-2-methylcyclopentan-1-one
• Synonyms: (2RS,1'SR)-2-(1',4'-dimethylcyclohex-3'-enyl)-2-methylcyclopentan-1-one
• CAS NO: 61375-52-8
• Molecular Weight: 206.328
• Mol File: 61375-52-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2RS,1'SR)-2-(1',4'-dimethylcyclohex-3'-enyl)-2-methylcyclopentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2RS,1'SR)-2-(1',4'-dimethylcyclohex-3'-enyl)-2-methylcyclopentan-1-one(61375-52-8)
• EPA Substance Registry System: (2RS,1'SR)-2-(1',4'-dimethylcyclohex-3'-enyl)-2-methylcyclopentan-1-one(61375-52-8)

Safety Data

• Hazardous Substances Data: 61375-52-8(Hazardous Substances Data)

Upstream product

• 74592-40-8 (3α,3aα,7aα)-3a,4,5,7a-Tetrahydro-3,3a,6-trimethyl-3-(4-hydroxybutyl)-2(3H)-benzofuranone 
• 62096-97-3 Methyl((1α,2α)-2-Hydroxy-1,4-dimethyl-3-cyclohexen-1-yl)-3-methyl-2-oxocyclopentanecarboxylate 
• 62096-98-4 Methyl 3-Methyl-3-(1-methyl-4-methylene-2-cyclohexenyl)-2-oxocyclopentanecarboxylate 
• 74592-48-6 4-((3R,3aS,7aS)-3,3a,6-Trimethyl-2-oxo-2,3,3a,4,5,7a-hexahydro-benzofuran-3-yl)-butyric acid 
• 74592-46-4 4-((3R,3aS,7aS)-3,3a,6-Trimethyl-2-oxo-2,3,3a,4,5,7a-hexahydro-benzofuran-3-yl)-butyraldehyde 
• 74592-45-3 (3β,3aβ,7aβ)-3a,4,5,7a-Tetrahydro-3,3a,6-trimethyl-3-(5-pentenyl)-2(3H)-benzofuranone 
• 74592-38-4 (3aR,7aR)-3a,6-Dimethyl-3-pent-4-enyl-3a,4,5,7a-tetrahydro-3H-benzofuran-2-one 
• 74592-37-3 (3-Bromo-1,4-dimethyl-2-oxo-cyclohexyl)-acetic acid ethyl ester 
• 37720-07-3 ethyl (1,4-dimethyl-2-oxocyclohex-3-enyl)acetate 
• 62096-99-5 2-Methyl-2-(1-methyl-4-methylene-2-cyclohexen-1-yl)-cyclopentanone 
• 37720-06-2 Ethyl 1,4-Dimethyl-2-oxo-1-cyclohexaneacetate 
• 37720-05-1 (1,4-Dimethyl-2-oxo-cyclohexyl)-acetic acid 
• 37720-03-9 1,4-Dimethyl-2-oxo-3-cyclohexeneacetic acid 
• 61476-32-2 (3α,3aα,7aα)-3a,4,5,7a-Tetrahydro-3,3a,6-trimethyl-2-(3H)-benzofuranone 

Downstream Products

• 61505-17-7 (+/-)-trichodiene 

Relevant articles and documents

Synthesis of (dl)-trichodiene using novel ring transformation reaction

Synthesis of (dl)-trichodiene has been completed via novel ring transformation reaction using TsOH/ethylene glycol.

Stereoselective Synthesis of (+/-)-Trichodiene

A stereoselective synthesis of (+/-)-trichodiene (1) is described whose key step is the conversion of the tricyclic, homoallylic alcohol 3, via β-fragmentation of its potassium alkoxide 3a, to cyclopentanone 2.

Stereoselective Total Synthesis of (+/-)-Trichodiene: Biogenetic Precursor of the Trichothecane Sesquiterpenoids

Two approaches to the total synthesis of (+/-)-trichodiene (1) are reported from cis-fused lactone 10.Sequential alkylation of lactone 10 was observed to be highly stereoselective as established by the construction of diastereomeric lactone esters 12 and