61379-88-2

Upstream product

• 108-24-7 acetic anhydride 
• 63260-82-2 ethyl 1-benzyl-4-phenylamino-4-piperidinecarboxylate 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 968-86-5 1-benzyl-4-(phenylamino)piperidine-4-carbonitrile 
• 62-53-3 aniline 

Downstream Products

• 79139-44-9 8-benzyl-1-phenyl-1,8-diazaspiro<4,5>decane-2,4-dione 
• 79139-51-8 1-phenyl-1,8-diazaspiro<4,5>decan-2-one 
• 79139-50-7 1-phenyl-1,8-diazaspiro<4,5>decan-4-one 
• 79139-47-2 8-Benzyl-1-phenyl-1,8-diaza-spiro[4.5]decan-4-ol 
• 79139-49-4 1-phenyl-1,8-diazaspiro<4,5>dec-3-enone-2 
• 79139-48-3 8-benzyl-1-phenyl-1,8-diazaspiro<4,5>decanone-4 
• 79139-46-1 8-benzyl-4-hydroxy-1-phenyl-1,8-diazaspiro<4,5>decanone-2 
• 79139-45-0 8-benzyl-4-methoxy-1-phenyl-1,8-diazaspiro<4,5>dec-3-en-2-one 
• 79139-52-9 1-phenyl-8<1'-(p-chlorophenyl)ethyl>-1,8-diazaspiro<4,5>decanone-4 

Relevant academic research and scientific papers

MUSCARINIC MODULATORS

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

RECEPTOR REGULATOR

A compound having a partial structure represented by the formula (A) (wherein ring Xa represents a nitrogen-containing ring and R represents optionally substituted amino) or a salt thereof. The compound or salt is highly effective in regulating neuromedin U receptors and is useful as a preventive/therapeutic agent for hypertension, etc.

THE SYNTHESIS OF 1,8-DIAZASPIRO-DECANES

The synthesis of some substituted 1,8-diazaspirodecanes starting from 1-benzyl-4-oxo-piperidine is described.This skeleton is isosteric to the 1,3,8-triazaspiro-decane structure present in important neuroleptic agents.