61382-42-1

Upstream product

• 103361-99-5 7-fluoro-3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 1040236-27-8 4-benzyl-7-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 75-16-1 methylmagnesium bromide 
• 53981-24-1 2-amino-5-fluorophenol 
• 137472-06-1 2-chloro-N-(4-fluoro-2-hydroxyphenyl)acetamide 

Downstream Products

• 1610610-90-6 4-(5-(7-fluoro-3-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-4-carbonyl)pyrazolo[1,5-a]pyridin-3-yl)-N-methylbenzamide 

Relevant academic research and scientific papers

PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS

Compounds of Formula (0), Formula (I), and Formula (II) and methods of use as Interleukin-1 Receptor Associated Kinase (IRAK4) inhibitors are described herein.

COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES

The present invention provides compounds of formula I: [INSERT FORMULA HERE] or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.