614-66-4

Usage

Uses

Used in Fragrance and Flavor Industry:
Piperonal is used as a fragrance ingredient in a wide range of personal care products, perfumes, and colognes due to its sweet, floral odor.
Used in Medicinal Applications:
Piperonal has been studied for its potential medicinal properties, including its ability to act as an insect repellent and as an antidepressant.
Used as a Precursor in Organic Synthesis:
Piperonal is also used as a precursor in the synthesis of other organic compounds.
Used in Insect Repellent Applications:
Piperonal has been studied for its potential as an insect repellent.
Used in Antidepressant Applications:
Piperonal has been studied for its potential as an antidepressant.
Note: Piperonal is a controlled substance in some countries due to its potential use in the illegal production of the drug MDMA.

Upstream product

• 120-57-0 piperonal 
• 67-64-1 acetone 
• 3160-37-0 4-(benzo[d][1,3]dioxol-5-yl)but-3-en-2-one 

Downstream Products

• 41186-48-5 2,5-bis-benzo[1,3]dioxol-5-yl-1-phenyl-1,2,3,5,6,7-hexahydro-pyrazolo[1,5-a]pyridine-6,7-dicarboxylic acid anhydride 
• 41296-80-4 5-benzo[1,3]dioxol-5-yl-3-(2-benzo[1,3]dioxol-5-yl-vinyl)-1-phenyl-4,5-dihydro-1H-pyrazole 

Relevant academic research and scientific papers

Synthesis of 2-(1,5-diaryl-1,4-pentadien-3-ylidene)- hydrazinecarboximidamide hydrochloride catalyzed by p-dodecylbenzenesulfonic acid in aqueous media under ultrasound irradiation

Amidinohydrazone compounds are very important synthetic intermediates and can serve as versatile precursors in synthesis of many natural products and drug molecules. The use of ultrasound, p-dodecylbenzenesulfonic acid (DBSA) and water as solvent improved the synthesis of different 2-(1,5-diaryl-1,4- pentadien-3-ylidene)-hydrazinecarboximidamide hydrochlorides. The best reaction conditions for the condensation of 1,5-diphenyl-1,4-pentadien-3-one with aminoguanidine hydrochloride were as follows: 1,5-diphenyl-1,4-pentadiene-3-one (1, 1 mmol), aminoguanidine hydrochloride (1.1 mmol), DBSA (0.5 mmol), water 10 mL, reaction temperature 25-27°C, irradiation frequency 25 kHz. 2a was achieved in 94% yield within 2 h. The other seven amidinohydrazones were obtained in 84-94% yield within 2-3 h under the same conditions. Compared to the method involving catalysis by hydrochloric acid in refluxing EtOH, the advantages of present procedure are milder conditions, shorter reaction times, higher yields, and environmental friendly conditions, which make it a useful strategy for the synthesis of analogues.