6140-61-0

Basic information

• Product Name: 2,2 DIMETHYL-4-CYANOBUTYRALDEHYDE
• Synonyms: 2,2 DIMETHYL-4-CYANOBUTYRALDEHYDE;4-CYANO-2,2-DIMETHYLBUTYRALDEHYDE;4,4-DIMETHYL-5-OXO-PENTANENITRILE;GAMMA-CYANO-ALPHA,ALPHA-DIMETHYLBUTYRALDEHYDE;Pentanenitrile, 4,4-dimethyl-5-oxo-;4-formyl-4-methylvaleronitrile;4,4-Dimethyl-5-oxovaleronitrile
• CAS NO: 6140-61-0
• Molecular Formula: C₇H₁₁NO
• Molecular Weight: 125.17
• EINECS: 228-125-8
• Mol File: 6140-61-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 93-95°C
• Flash Point: 90.7°C
• Appearance: /
• Density: 0.928g/cm³
• Vapor Pressure: 0.0819mmHg at 25°C
• Refractive Index: 1.425
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Dichloromethane (Slightly)
• CAS DataBase Reference: 2,2 DIMETHYL-4-CYANOBUTYRALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2 DIMETHYL-4-CYANOBUTYRALDEHYDE(6140-61-0)
• EPA Substance Registry System: 2,2 DIMETHYL-4-CYANOBUTYRALDEHYDE(6140-61-0)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3276
• HazardClass: IRRITANT
• Hazardous Substances Data: 6140-61-0(Hazardous Substances Data)

Usage

Uses

4,4-Dimethyl-5-oxopentanenitrile is a useful reagent for the preparation of psoracorylifol analogs.

InChI:InChI=1/C7H11NO/c1-7(2,6-9)4-3-5-8/h6H,3-4H2,1-2H3

Upstream product

• 107-13-1 acrylonitrile 
• 78-84-2 isobutyraldehyde 
• 126554-00-5 N-[1-(E)-penten-1-yl]pyrrolidine 
• 19251-77-5 1-Cyano-2-dimethylamino-3,3-dimethyl-cyclobutan 

Downstream Products

• 100380-11-8 5-(4-chloro-phenyl)-5-hydroxy-4,4-dimethyl-valeronitrile 
• 288296-24-2 [(1S,2R)-1-Benzyl-3-(4-cyano-2,2-dimethyl-butylamino)-2-hydroxy-propyl]-carbamic acid (3R,3aS,6aR)hexahydro-furo[2,3-b]furan-3-yl ester 
• 25252-68-0 4,4-dimethyl-5-hydroxyvaleronitrile 
• 82560-12-1 5-(tert-butyl)-1H-pyrazol-3-amine 
• 942347-52-6 C₂₁H₃₄N₂O 
• 1256920-58-7 1-{3-[(4-bromophenyl)oxy]propyl}-3,3-dimethylpiperidine 
• 33328-58-4 2,5-Bis(1,1-dimethylbutyl)thiazolo<5,4-d>thiazol 
• 27579-09-5 Amido-4-dimethyl-4,4-buttersaeure 
• 4786-23-6 4-methyl-3-pentenenitrile 
• 102952-23-8 5-hydroxy-4,4-dimethyl-1,5-diphenyl-pentan-1-one-(2,4-dinitro-phenylhydrazone) 
• 102156-99-0 toluene-4-sulfonic acid-(4-cyano-2,2-dimethyl-1-phenyl-butyl ester) 
• 106475-56-3 5-(3,5-dinitro-benzoyloxy)-4,4-dimethyl-valeronitrile 
• 101115-48-4 toluene-4-sulfonic acid-(4-cyano-2,2-dimethyl-butyl ester) 
• 53783-86-1 3,3-dimethylcyclobutane-1-carbonitrile 

Relevant articles and documents

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STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION

The invention relates to the use of amidoximes for prevention of or stabilization of hydroxylamine compounds against undesired decomposition.

Inhibitors of aspartyl protease

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.