6140-61-0

Usage

Uses

Used in Pharmaceutical Industry:
2,2-DIMETHYL-4-CYANOBUTYRALDEHYDE is used as a synthetic intermediate for the preparation of psoracorylifol analogs, which are compounds with potential therapeutic applications. Its reactivity and functional groups make it a versatile building block in the development of new pharmaceutical agents.
Used in Chemical Research:
In the field of chemical research, 2,2-DIMETHYL-4-CYANOBUTYRALDEHYDE is employed as a reagent for the synthesis of various organic compounds. Its unique structure allows for a wide range of chemical reactions, making it a valuable tool for exploring new chemical pathways and developing novel compounds with diverse applications.

InChI:InChI=1/C7H11NO/c1-7(2,6-9)4-3-5-8/h6H,3-4H2,1-2H3

Upstream product

• 107-13-1 acrylonitrile 
• 78-84-2 isobutyraldehyde 
• 19251-77-5 1-Cyano-2-dimethylamino-3,3-dimethyl-cyclobutan 
• 126554-00-5 N-[1-(E)-penten-1-yl]pyrrolidine 

Downstream Products

• 100380-11-8 5-(4-chloro-phenyl)-5-hydroxy-4,4-dimethyl-valeronitrile 
• 6939-69-1 α,α-Dimethyl-γ-cyanobuttersaeure 
• 288296-24-2 [(1S,2R)-1-Benzyl-3-(4-cyano-2,2-dimethyl-butylamino)-2-hydroxy-propyl]-carbamic acid (3R,3aS,6aR)hexahydro-furo[2,3-b]furan-3-yl ester 
• 4786-23-6 4-methyl-3-pentenenitrile 
• 27579-09-5 Amido-4-dimethyl-4,4-buttersaeure 
• 681-57-2 2,2-dimethylglutaric acid 
• 25252-68-0 4,4-dimethyl-5-hydroxyvaleronitrile 
• 542-54-1 isocapronitrile 
• 1193-12-0 3,3-dimethylpiperidine 
• 20633-33-4 4,4-Dimethyl-5-hydroxy-5-phenyl-pentanonitril 
• 82560-12-1 5-(tert-butyl)-1H-pyrazol-3-amine 
• 942347-52-6 C₂₁H₃₄N₂O 
• 1256920-58-7 1-{3-[(4-bromophenyl)oxy]propyl}-3,3-dimethylpiperidine 
• 33328-58-4 2,5-Bis(1,1-dimethylbutyl)thiazolo<5,4-d>thiazol 

Relevant academic research and scientific papers

Development of the route of manufacture of an oral H1-H 3 antagonist

A new route to an H1-H3 antagonist was developed to address scalability and environmental and cost of goods issues associated with the initial route.

STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION

The invention relates to the use of amidoximes for prevention of or stabilization of hydroxylamine compounds against undesired decomposition.

Syntheses and biological evaluation of vinblastine congeners.

Sixty-two congeners of vinblastine (VLB), primarily with modifications of the piperidine ring in the carbomethoxycleavamine moiety of the binary alkaloid, were synthesized and evaluated for cytotoxicity against murine L1210 leukemia and RCC-2 rat colon cancer cells, and for their ability to inhibit polymerization of microtubular protein at 10(7) M concentrations was found for L1210 inhibition by these compounds, with the most active 1000x as potent as vinblastine.

Inhibitors of aspartyl protease

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.

Ketone precursors for organoleptic compounds

The invention discloses ketones of formula I: wherein, Y is an optionally substituted alkyl, cycloalkyl, or cycloalkylalkyl, wherein each alkyl group is straight or branched and each alkyl and cycloalkyl group is saturated or unsaturated; R1is hydrogen or a C1-6alkyl group that is substituted, saturated or unsaturated, straight or branched; A is a chromophoric substituted aromatic ring or ring system; n is an integer; and with the proviso that formula I is not 2-ethoxy-1-phenyl-ethanone. These compositions are useful for the delivery of organoleptic compounds, especially of flavors, fragrances, masking agents and antimicrobial compounds.

Synthesis of vinblastine and vincristine type compounds

A new process for the stereospecific synthesis of alkaloids of the vinblastine and vincristine type including the synthesis of vinblastine and vincristine as well novel alkaloids which are active as anti-tumor agents.