6141-96-4

Basic information

• Product Name: ethyl [4-oxo-5-(pyridin-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-3-yl]acetate
• CAS NO: 6141-96-4
• Molecular Formula: C₁₂H₉BrN₂
• Molecular Weight: 308.376
• Mol File: 6141-96-4.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 455.2°C at 760 mmHg
• Flash Point: 229.1°C
• Density: 1.43g/cm³
• Vapor Pressure: 1.8E-08mmHg at 25°C
• Refractive Index: 1.67
• CAS DataBase Reference: ethyl [4-oxo-5-(pyridin-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-3-yl]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl [4-oxo-5-(pyridin-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-3-yl]acetate(6141-96-4)
• EPA Substance Registry System: ethyl [4-oxo-5-(pyridin-3-ylmethylidene)-2-thioxo-1,3-thiazolidin-3-yl]acetate(6141-96-4)

Safety Data

• Hazardous Substances Data: 6141-96-4(Hazardous Substances Data)

Upstream product

• 53547-13-0 cis-(4-bromo-phenyl)-phenyl-diazene 
• 98-95-3 nitrobenzene 
• 106-40-1 4-bromo-aniline 
• 4418-84-2 4-bromoazobenzene 
• 586-96-9 Nitrosobenzene 
• 7466-30-0 1-(4-bromophenyl)-1,2-diphenylhydrazine 
• 62-53-3 aniline 
• 3958-47-2 triphenylindium 
• 3623-23-2 4-bromonitrosobenzene 
• 7522-27-2 m-Chlor-N.N--anilin 
• 5089-33-8 2-(4-bromophenyl)-1,1,1,3,3,3-hexamethyldisilazane 
• 64-17-5 ethanol 
• 16109-68-5 4-bromo-1-phenyl-NNO-azoxybenzene 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 16109-68-5 (Z)-N-(4-bromo-phenyl)-N'-phenyl-diazene-N-oxide 
• 16054-48-1 (Z)-2-(4-bromophenyl)-1-phenyldiazene 1-oxide 
• 7466-30-0 1-(4-bromophenyl)-1,2-diphenylhydrazine 
• 1601-98-5 (E)-bis(4-bromophenyl)diazene 
• 53547-13-0 cis-(4-bromo-phenyl)-phenyl-diazene 

Relevant articles and documents

Zr(OH)4-Catalyzed Controllable Selective Oxidation of Anilines to Azoxybenzenes, Azobenzenes and Nitrosobenzenes

The selective oxidation of aniline to metastable and valuable azoxybenzene, azobenzene or nitrosobenzene has important practical significance in organic synthesis. However, uncontrollable selectivity and laborious synthesis of the expensive required catalysts severely hinders the uptake of these reactions in industrial settings. Herein, we have pioneered the discovery of Zr(OH)4 as an efficient heterogeneous catalyst capable of the selective oxidation of aniline, using either peroxide or O2 as oxidant, to selectively obtain various azoxybenzenes, symmetric/unsymmetric azobenzenes, as well as nitrosobenzenes, by simply regulating the reaction solvent, without the need for additives. Mechanistic experiments and DFT calculations demonstrate that the activation of H2O2 and O2 is primarily achieved by the bridging hydroxyl and terminal hydroxyl groups of Zr(OH)4, respectively. The present work provides an economical and environmentally friendly strategy for the selective oxidation of aniline in industrial applications.

Oxidative dehydrogenation of hydrazines and diarylamines using a polyoxomolybdate-based iron catalyst

We report an efficient method for the oxidative dehydrogenation of hydrazines and diarylamines in aqueous ethanol using Anderson-type polyoxomolybdate-based iron(iii) as a catalyst and hydrogen peroxide as an oxidant. A series of azo compounds and tetraarylhydrazines were obtained in moderate to excellent yields. The reaction conditions and substrate scopes are complementary or superior to those of more established protocols. In addition, the catalyst shows good stability and reusability in water. The preliminary mechanistic studies suggest that a radical process is involved in the reaction.

Electrochemical dehydrogenation of hydrazines to azo compounds

A strategy for the electrochemical dehydrogenation of hydrazine compounds is disclosed under ambient conditions. This protocol proceeded smoothly in ethanol by employing electrons as clean oxidants. Its synthetic value is well demonstrated by the highly efficient synthesis of symmetric and unsymmetric azo compounds. It is an environmentally friendly transformation and the present protocol was effective on a large scale.