6141-98-6

Basic information

• Product Name: BENZO[C]CINNOLINE N-OXIDE
• Synonyms: BENZO[C]CINNOLINE N-OXIDE;benzo(c)cinnoline,5-oxide;cp6875;Benzocücinnoline N-oxide, 95%;Benzocinnolineoxide
• CAS NO: 6141-98-6
• Molecular Formula: C₁₂H₈N₂O
• Molecular Weight: 196.2
• EINECS: 228-134-7
• Mol File: 6141-98-6.mol
• Article Data: 20

Chemical Properties

• Melting Point: 139-140°C
• Boiling Point: 409.3 °C at 760 mmHg
• Flash Point: 201.4 °C
• Appearance: yellow crystal powder
• Density: 1.28 g/cm³
• Vapor Pressure: 1.55E-06mmHg at 25°C
• Refractive Index: 1.683
• PKA: -0.57±0.50(Predicted)
• BRN: 8732
• CAS DataBase Reference: BENZO[C]CINNOLINE N-OXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZO[C]CINNOLINE N-OXIDE(6141-98-6)
• EPA Substance Registry System: BENZO[C]CINNOLINE N-OXIDE(6141-98-6)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• RTECS: DE7644000
• Hazardous Substances Data: 6141-98-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 25, p. 736, 1960 DOI: 10.1021/jo01075a016Tetrahedron Letters, 34, p. 877, 1993 DOI: 10.1016/0040-4039(93)89037-Q

InChI:InChI=1/C12H8N2O/c15-14-12-8-4-2-6-10(12)9-5-1-3-7-11(9)13-14/h1-8H

Upstream product

• 230-17-1 benzo[c]cinnoline 
• 2436-96-6 1-nitro-2-(2-nitrophenyl)benzene 
• 17613-50-2 (2'-nitro-biphenyl-2-yl)-carbamic acid ethyl ester 
• 7052-12-2 benzo[c]cinnoline-N,N'-dioxide 
• 35883-86-4 2-amino-2'-nitrobiphenyl 
• 56-81-5 glycerol 
• 17294-89-2 2'-nitro-biphenyl-2-carboxylic acid 
• 29722-92-7 2'-nitro-biphenyl-2-carboxylic acid amide 
• 71237-36-0 2'-nitrobiphenyl acid chloride 
• 13463-40-6 iron pentacarbonyl 
• 98-95-3 nitrobenzene 
• 95-51-2 o-chloroaniline 
• 62-53-3 aniline 

Downstream Products

• 7090-45-1 octachlorobiphenylene 
• 1620101-19-0 4-(4-methylphenylsulfonamido)benzo[c]cinnoline 5-oxide 
• 854637-47-1 N-benzo[c]cinnolin-2-yl-N-(2-diethylamino-ethyl)-toluene-4-sulfonamide 
• 854637-54-0 N-benzo[c]cinnolin-2-yl-toluene-4-sulfonamide 
• 4827-07-0 2-Amino-benzocinnolin 
• 60-80-0 antipyrine 
• 230-17-1 benzo[c]cinnoline 
• 259-79-0 bisbenzocyclobutene 
• 81709-93-5 7-(Octahydro-9aH-trans-benzocycloocta<3,4>pyrazolo<1,2-a>cinnolin-16-yl)heptanal 

Relevant articles and documents

A practical synthesis of substituted benzo[c]cinnoline- N,N′-dioxides and N-oxides

A practical synthesis of variously substituted benzo[c]cinnoline-N,N′-dioxides and N-oxides is described, based on the reduction of the appropriate o,o′-dinitrobiphenyl compound with KOH in refluxing 2-propanol.

NOVEL PREPARATION METHOD OF QUINOLINE N-OXIDE DERIVATIVE WITH AMIDE GROUP

Provided are a preparation method of a quinoline N-oxide derivative with an amide group capable of easily introducing the amide group into the quinoline N-oxide derivative by simplified processes and mild reaction conditions, and a quinoline N-oxide derivative with an amide group prepared by using the same.

Transition-Metal-Free Cross-Coupling Reactions by Single Electron Transfer (SET)

A facile, efficient, single-step protocol for the synthesis of cinnoline derivatives by a transition-metal-free coupling between amino- and nitroaryl compounds by single electron transfer (SET) has been developed. Direct carbon-carbon bond formation was achieved from nonfunctionalized aromatic carbon atoms. A plausible mechanism has been proposed.