61443-77-4 Usage
Uses
Used in Pharmaceutical Industry:
8-Hydroxyloxapine is used as a metabolite in the development and understanding of atypical antipsychotic medications. Its role in the metabolism of loxapine provides insights into the drug's efficacy and potential side effects, contributing to the optimization of antipsychotic treatments.
Used in Research and Development:
8-Hydroxyloxapine serves as a valuable compound for researchers studying the mechanisms of action and receptor interactions of atypical antipsychotic drugs. Its relatively low affinity for dopamine and 5-HT receptors makes it a useful tool for investigating the contributions of these receptors to the therapeutic effects and side effects of loxapine.
Used in Drug Metabolism Studies:
8-Hydroxyloxapine is used as a subject in drug metabolism studies to understand the role of cytochrome P450 isoform CYP1A2 in the metabolism of atypical antipsychotic medications. This knowledge can help in the development of personalized medicine approaches, tailoring drug treatments to individual patients based on their unique metabolic profiles.
Used in Drug Interaction Studies:
8-Hydroxyloxapine can be employed in studies investigating potential drug interactions involving loxapine and other medications that are metabolized by the same cytochrome P450 isoform, CYP1A2. Understanding these interactions can help healthcare providers make informed decisions about drug combinations and dosing regimens to maximize therapeutic benefits and minimize adverse effects.
Check Digit Verification of cas no
The CAS Registry Mumber 61443-77-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,4,4 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 61443-77:
(7*6)+(6*1)+(5*4)+(4*4)+(3*3)+(2*7)+(1*7)=114
114 % 10 = 4
So 61443-77-4 is a valid CAS Registry Number.
InChI:InChI=1/C18H18ClN3O2/c1-21-6-8-22(9-7-21)18-14-10-12(19)2-4-16(14)24-17-5-3-13(23)11-15(17)20-18/h2-5,10-11,23H,6-9H2,1H3
