61448-75-7

Upstream product

• 61448-83-7 (3Z,5Z)‐3,5‐bis({[3‐(trifluoromethyl)phenyl]methylidene})‐1λ6‐thiane‐1,1,4‐trione 
• 454-89-7 3-Trifluoromethylbenzaldehyde 
• 61448-74-6 7-(3-trifluoromethyl-benzylidene)-3-(3-trifluoromethyl-phenyl)-2,3,3a,4,6,7-hexahydro-thiopyrano[4,3-c]pyrazole 5,5-dioxide 

Downstream Products

• 83319-85-1 2-acetyl-2,3,3a,4,6,7-hexahydro-3-[3-(trifluoromethyl)phenyl]-7-{[3-(trifluoromethyl)phenyl]methyl}thiopyrano[4,3-c]pyrazole 5,5-dioxide 

Relevant academic research and scientific papers

Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues

A series of novel hexahydrothiopyrano[4,3-c]pyrazoles and related analogues were prepared and tested for antiinflammatory activity by using the mouse active Arthus reaction and the delayed hypersensitivity skin reaction in guinea pigs as primary screens.

Thiopyrano[4,3-c] pyrazoles

Anti-inflammatory activity is exhibited by compounds having the formula SPC1 The salts thereof, and the 5-oxide and 5,5-dioxide thereof, wherein R1 is hydrogen, alkyl, aryl, arylalkyl, or acyl; and R2 and R3 are the same o