614753-33-2Relevant academic research and scientific papers
Base-mediated reactions of N-alkyl-O-acyl hydroxamic acids: Synthesis of 3-oxo-2,3-dihydro-4-isoxazole carboxylic ester derivatives
Clark, Andrew J.,Patel, Divya,Broadhurst, Michael J.
, p. 7763 - 7765 (2003)
Treatment of malonyl derived O-acyl hydroxamic acid derivatives 10a-h with the phosphazene super base P-2-t-Bu 7 gives 2,3-dihydro-4-isoxazole carboxylic ester derivatives 11a-h. The rate and yield of the reaction is dependent upon the O-acyl substituent.
