69479-87-4Relevant articles and documents
MALONIC ESTER DERIVATIVES OF HETEROARYLPIPERIDINES AND -PIPERAZINES AS FUNGICIDES
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Page/Page column 64, (2015/03/16)
Malonic ester derivatives of the formula (I), in which the symbols A1, A2, Y R10, p, X, R2, G, Q, L2 and R1 are each as defined in the description, and salts, metal complexes and N-oxides of the compounds of the formula (I), and the use thereof for controlling phytopathogenic harmful fungi and processes for preparing compounds of the formula (I).
Photochemical and thermal [2 + 2] cycloaddition to generate the bicyclo[3.2.0]heptane core of bielschowskysin
Farcet, Jean-Baptiste,Himmelbauer, Martin,Mulzer, Johann
supporting information, p. 4379 - 4398 (2013/07/26)
A bicyclic core fragment of the marine diterpenoid bielschowskysin has been synthesized. First, a large library of precursors for a photochemical [2 + 2] cycloaddition was prepared and tested, but with limited success. In the end, a thermal [2 + 2] cycloaddition followed by appropriate regio-and stereocontrolled functionalization efficiently gave access to the desired bicyclo[3.2.0]heptane core. An optimized route to this remarkable molecular structure is presented. Copyright
Short and versatile route to a key intermediate for lactacystin synthesis.
Bulman Page, Philip C,Hamzah, A Sazali,Leach, David C,Allin, Steven M,Andrews, David M,Rassias, Gerasimos A
, p. 353 - 355 (2007/10/03)
[reaction: see text] A key intermediate 14 for the synthesis of lactacystin 1 has been constructed in four steps and 33% overall yield. The key steps involve cyclization of a suitably functionalized glutamic acid derivative and concomitant alkylation of the resulting beta,beta-diketoester system, C-acylation of the cyclic alpha-amidoketone 9, and decarboxylbenzylation of 12. Alkylation of a related beta,beta-diketoester 5 was additionally achieved with several electrophiles.
A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid
Page, Philip C. Bulman,Leach, David C.,Hayman, Colin M.,Hamzah, A. Sazali,Allin, Steven M.,McKee, Vickie
, p. 1025 - 1027 (2007/10/03)
An advanced intermediate 22 for lactacystin synthesis, containing the full carbon skeleton of the pyrrolidinone component, has been achieved in four steps from a protected glycine ester.
New trisubstituted cyclopentadienyl ligands: Synthesis, characterisation and catalytic properties of mono and dinuclear cobalt, rhodium, iron and ruthenium complexes
Costa, Mirco,Dalcanale, Enrico,Dias, Francisco Santos,Graiff, Claudia,Tiripicchio, Antonio,Bigliardi, Lorenzo
, p. 179 - 193 (2007/10/03)
The synthesis of a set of dialkyl 4-alkoxycarbonylcyclopenta-1,3-diene-1,2-diacetates (1a-e) is described. Their coordinating abilities as anions have been investigated in relation to the formation of new sandwich, half-sandwich and dinuclear complexes and their structural features. We report here the preparation and characterisation of some complexes such as a mononuclear half-sandwich cobalt(1,5-COD) complex which has shown to be a very efficient catalyst for the cyclocotrimerisation reaction of alkynes and nitriles to pyridines. Half-sandwich rhodiumdicarbonyl complexes containing trisubstituted cyclopentadienyl ligands with ester chains of different length have been employed successfully as catalysts for hydroformylation of styrene. Finally ligands 1a-e have been used for the synthesis of ferrocenes and dinuclear carbonyl complexes of iron and ruthenium. The structures of the complexes 1,5-cycloctadiene[1-methoxycarbonyl-3,4-di(methoxycarbonylmethylene) cyclopentadienyl]cobalt [Co(MDMCp)COD] (9), dicarbonyl[1-methoxycarbonyl-3,4-di(methoxycarbonylmethylene)cyclopentadienyl] rhodium [Rh(MDMCp)(CO)2] (2a) and of a new ferrocene complex [Fe(MDMCp)2] (15a) have been determined by X-ray diffraction methods.
The use of γ-turn mimetics to define peptide secondary structure
Callahan,Newlander,Burgess,Eggleston,Nichols,Wong,Huffman
, p. 3479 - 3488 (2007/10/02)
A novel γ-turn mimetic 2 has been prepared based on retro amide peptide design. Incorporation of this mimetic into linear peptide fibrinogen receptor antagonist 7 (GPIIb/IIIa receptor) affords the opportunity to test models of antagonist pharmacophore.