614760-54-2Relevant academic research and scientific papers
Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering
Erlanson, Daniel A.,McDowell, Robert S.,He, Molly M.,Randal, Mike,Simmons, Robert L.,Kung, Jenny,Waight, Andrew,Hansen, Stig K.
, p. 5602 - 5603 (2007/10/03)
Protein tyrosine phosphatases play important roles in many signaling cascades involved in human disease. The identification of druglike inhibitors for these targets is a major challenge, and the discovery of suitable phosphotyrosine (pY) mimetics remains
