61491-01-8Relevant academic research and scientific papers
I2/Li2CO3-promoted cyanation of diarylalcohols through a dual activation process
Hu, Liangzhen,Hussain, Muhammad Ijaz,Deng, Qingfu,Liu, Qing,Feng, Yangyang,Zhang, Xiaohui,Xiong, Yan
, p. 308 - 314 (2018/12/11)
One-step base promoted strategy for cyanation of α,α-diaryl alcohols has been developed under mild and transition metal-free conditions. This method provides a straightforward and facile way towards the synthesis of β,γ-unsaturated nitriles and α-phenylnitiriles from α-vinyl carbinols and α,α-diaryl methanols, respectively, up to 99% yield. Moreover, various azides and ethers could also be accessed from their respective nucleophiles under standard reaction conditions.
Copper-catalyzed trifluoromethylation-initiated radical 1,2-aryl migration in α,α-diaryl allylic alcohols
Liu, Xiaowu,Xiong, Fei,Huang, Xuanping,Xu, Liang,Li, Pengfei,Wu, Xiaoxing
, p. 6962 - 6966 (2013/07/26)
Not only symmetrical, but also unsymmetrical α,α-diaryl allylic alcohols are employed as substrates in the title reaction. A number of arenes and even heteroarenes underwent radical 1,2-aryl migration ("neophyl rearrangement") to produce α-aryl β-trifluoromethyl ketones. The preferential migration of electron-deficient aryl groups over electron-rich ones in unsymmetrical substrates supports the radical mechanism, which was further confirmed by DFT calculations. Copyright
(E)-α-Iodovinylstannanes as convenient precursors for stereoselective synthesis of trisubstituted alkenes
Cai, Mingzhong,Ye, Hongde,Zhao, Hong,Song, Caisheng
, p. 465 - 467 (2007/10/03)
Based on the different reactivities of iodo-groups and tributylstannyl groups, (E)-α-iodovinylstannanes can undergo sequential cross-coupling reactions in the presence of a palladium(0) catalyst to form two carbon-carbon bonds to the same olefinic carbon leading to trisubstituted alkenes stereoselectively.
