61499-22-7Relevant academic research and scientific papers
DDQ-mediated oxidation of allylarenes: Expedient access to cinnamaldehyde-containing phenylpropanoids
Jiang, Tao-Shan,Zhang, Qingqing,Li, Guohui,Cheng, Xi,Cai, Yongping
, p. 4611 - 4616 (2019/02/01)
Phenylpropanoid natural products containing a cinnamaldehyde motif were easily synthesized from allylarenes mediated by 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) oxidation. Representative examples described herein are five types of 4-hydroxycinnamaldehyde derivatives from monolignols biosynthesis, Boropinal C, and 7-methoxywutaifuranal from plant extracts. Especially, simple synthesis of 7-methoxywutaifuranal was exploited through selective mono-oxidation and subsequent isomerization-ring-closing-metathesis strategy.
NITRIC OXIDE DONOR NEPRILYSIN INHIBITORS
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Paragraph 0390; 0391, (2014/01/07)
In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, R7, R8, Z, X, b, and c are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are nitric oxide donors and have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
The synthesis of phenolic propane-1, 2- and 1,3-diols as intermediates in immobilised chelatants for the borate anion
Tyman, John H. P.,Payne
, p. 691 - 695 (2007/10/03)
The isomeric 3-(hydroxyphenyl)propane-1, 2-diols have been synthesised from allylic precursors by epoxidation and cleavage. Several different methods have been examined for obtaining 1-(methoxyphenyl)propane-1, 3-diols. 2-(methoxyphenyl)propane-1, 3-diols and certain hydroxy analogues have been obtained from benzaldoximes converted by oxidation to methoxy- and benzyloxynitromethylbenzenes followed by hydroxymethylation with formaldehyde and catalytic hydrogenation.
NO-donor phenols: A new class of products endowed with antioxidant and vasodilator properties
Boschi, Donatella,Tron, Gian Cesare,Lazzarato, Loretta,Chegaev, Konstantin,Cena, Clara,Di Stilo, Antonella,Giorgis, Marta,Bertinaria, Massimo,Fruttero, Roberta,Gasco, Alberto
, p. 2886 - 2897 (2007/10/03)
The synthesis and study of the antioxidant and vasodilator properties of a new class of phenols able to release nitric oxide are described. The products were designed through a symbiotic approach using selected phenols and selected nitrooxy and furoxan NO
FeCl3-adsorbed on montmorillonite K-10: An efficient catalyst for one-pot dealkylation-acetylation of ethers
Lakouraj, Mansour,Movassagh, B.,Fasihi, J.
, p. 378 - 379 (2007/10/03)
Direct conversion of ethers into acetates is achieved by treatment of ethers with acetic anhydride in the presence of FeCl3-adsorbed on montmorillonite K-10.
