61521-74-2 Usage
Description
(3R)-3β,4α-Bis(3-methoxy-4-hydroxybenzyl)-3-hydroxytetrahydrofuran-2-one, also known as tetrahydrocurcumin, is a naturally occurring compound found in the rhizomes of the turmeric plant (Curcuma longa). It is a derivative of curcumin, the active ingredient in turmeric, and is known for its antioxidant, anti-inflammatory, and anti-cancer properties.
Used in Pharmaceutical Industry:
Tetrahydrocurcumin is used as a therapeutic agent for its potential health benefits, including its ability to reduce oxidative stress, inhibit inflammation, and provide protection against various chronic diseases.
Used in Skincare Industry:
Tetrahydrocurcumin is used as a treatment for various skin disorders due to its anti-inflammatory and antioxidant properties.
Used in Diabetes Treatment:
Tetrahydrocurcumin is used as a therapeutic agent for diabetes, as it has been studied for its potential to improve insulin sensitivity and glucose metabolism.
Used in Neurodegenerative Disease Treatment:
Tetrahydrocurcumin is used as a potential therapeutic agent for neurodegenerative diseases, as it has been investigated for its potential to protect against neuronal damage and improve cognitive function.
Used in Cancer Treatment:
Tetrahydrocurcumin is used as a potential therapeutic agent in the treatment of various types of cancer, as it has been studied for its ability to inhibit cancer cell growth and induce apoptosis.
Check Digit Verification of cas no
The CAS Registry Mumber 61521-74-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,5,2 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 61521-74:
(7*6)+(6*1)+(5*5)+(4*2)+(3*1)+(2*7)+(1*4)=102
102 % 10 = 2
So 61521-74-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H22O7/c1-25-17-8-12(3-5-15(17)21)7-14-19(23)27-11-20(14,24)10-13-4-6-16(22)18(9-13)26-2/h3-6,8-9,14,21-22,24H,7,10-11H2,1-2H3/t14-,20-/m0/s1
61521-74-2Relevant articles and documents
Radical and superoxide scavenging activities of matairesinol and oxidized matairesinol
Yamauchi, Satoshi,Sugahara, Takuya,Nakashima, Yuki,Okada, Akihiro,Akiyama, Koichi,Kishida, Taro,Maruyama, Masashi,Masuda, Toshiya
, p. 1934 - 1940 (2008/02/08)
The radical and superoxide scavenging activities of oxidized matairesinols were examined. It could be assumed that the free benzylic position was important for higher radical scavenging activity. The different level of activity was observed between 7′-oxomatairesinol (Mat 2) and 7-oxomatairesinol (Mat 3). The activity of 8-hydroxymatairesinol was lower than that of matairesinol (Mat 1). The superoxide scavenging activity of the oxidized matairesinols was also demonstrated for the first time. It is assumed that the pKa value of phenol in the oxidized matairesinols affected this activity.
Synthesis of (+)-wikstromol by double alkylation of malic acid
Sefkow, Michael
, p. 987 - 989 (2007/10/03)
The synthesis of (+)-wikstromol in six steps, based on two stereoselective benzylations of unnatural malic acid derivatives, is presented. The influence of the alkyl ester on yield and selectivity in the alkylation of malic acid esters is examined.
TOTAL SYNTHESES OF (-)-TRACHELOGENIN, (-)-NORTRACHELOGENIN AND (+)-WIKSTROMOL
Khamlach, Kenza,Dhal, Robert,Brown, Eric
, p. 2221 - 2224 (2007/10/02)
The title compounds were obtained by α-hydroxylation of the corresponding α,β-dibenzyl-γ-butyrolactones (lignans of synthetic origin), and were correlated to (+/-)-methyltrachelogenin 9 whose relative structure was definitely established by X-ray cristallography. (-)-Trachelogenin 1 and (-)-nortrachelogenin 12 thus have the (8S,8'S) absolute configuration, whereas (+)-nortrachelogenin 20 (or wikstromol) has the (8R,8'R) absolute configuration.