615250-57-2

Upstream product

• 161469-43-8 (S)-3-((tert-butyldiphenylsilyl)oxy)propane-1,2-diol 
• 3282-30-2 pivaloyl chloride 
• 98-59-9 p-toluenesulfonyl chloride 
• 615250-55-0 2,2-dimethyl-propionic acid 3-(tert-butyl-diphenyl-silanyloxy)-2-hydroxy-propyl ester 

Downstream Products

• 615250-70-9 2,2-Dimethyl-propionic acid (R)-3-((2S,4R,5S,6R)-5-acetoxy-4-dimethylamino-6-methyl-tetrahydro-pyran-2-yloxy)-2-(toluene-4-sulfonyloxy)-propyl ester 
• 615250-74-3 2,2-Dimethyl-propionic acid (R)-3-((2R,4R,5S,6R)-5-acetoxy-4-dimethylamino-6-methyl-tetrahydro-pyran-2-yloxy)-2-(toluene-4-sulfonyloxy)-propyl ester 
• 615250-61-8 2,2-Dimethyl-propionic acid (R)-3-hydroxy-2-(toluene-4-sulfonyloxy)-propyl ester 

Relevant academic research and scientific papers

Glycidol-carbohydrate hybrids: A new family of DNA alkylating agents

Novel and chiral glycidol-carbohydrate hybrids possessing an epoxy group as a DNA alkylating moiety were designed and synthesized. These artificial hybrids selectively alkylated DNA at the N-7 sites of the guanines and cleaved DNA without any additives. The binding ability of the glycidol was significantly enhanced by the attachment of the carbohydrate.