615268-03-6Relevant articles and documents
Hydroxamate based inhibitors of adenylyl cyclase. Part 1: The effect of acyclic linkers on P-site binding
Levy, Daniel E,Marlowe, Charles,Kane-Maguire, Kim,Bao, Ming,Cherbavaz, Diana B.,Tomlinson, James E.,Sedlock, David M.,Scarborough, Robert M.
, p. 3085 - 3088 (2002)
The adenylyl cyclases (ACs) are a family of enzymes that are key elements of signal transduction by virtue of their ability to convert ATP to cAMP. The catalytic mechanism of this transformation proceeds through initial binding of ATP to the purine bindin
PYRANOPYRAZOLE AND PYRAZOLOPYRIDINE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES
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Paragraph 0450; 0451, (2019/06/17)
Pyranoyrazoles and pyrazolopyridines of formula I or formula II are disclosed: (I), (II) These compounds inhibit Coagulation Factor Xlla in the presence of thrombin and other coagulation factors. They are useful to treat autoimmune diseases.