61533-14-0Relevant academic research and scientific papers
Transformations des enamines α-formylees: Synthese d'α-amino esters N,N-disubstitues
Rulev, Alexander Yu.,Larina, Lyudmila I.,Voronkov, Mikhail G.
, p. 10211 - 10214 (2000)
2-Dialkylaminoalkanoic esters are prepared in moderate yield by the reaction of N,N-disubstituted 2-amino-2-alkenals with dialkyl phosphonates in the presence of sodium alkoxide. A mechanism involving an α-keto-β-aminophosphonate as an intermediate is proposed. (C) 2000 Elsevier Science Ltd.
Copper-catalyzed amination of ketene silyl acetals with hydroxylamines: Electrophilic amination approach to α-amino acids
Matsuda, Naoki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
, p. 11827 - 11831 (2013/01/15)
Role reversal: The title reaction has been developed to deliver α-amino acids under very mild reaction conditions (see scheme; dpppen=1,5-bis(diphenylphosphino)pentane). The catalysis provides a new C-N bond-forming approach for the synthesis of α-amino a
SYNTHESE ORGANOMETALLIQUE D'α-AMINOESTERS N,N-DISUBSTITUES
Bourhis, Mireille,Bosc, Jean-Jacques,Golse, Rene
, p. 193 - 202 (2007/10/02)
Reaction of organozinc compounds with a particular gem-aminoether ester, i.e. methyl-N,N-diethylamino methoxyacetate, leads to α-aminoesters.This method allows the synthesis of compounds having potential biological activity, viz. β-unsaturated α-aminoesters.
