615538-49-3

Upstream product

• 501440-99-9 ethyl 5-((5-nitroindol-2-yl)carbonyl)aminoindole-2-carboxylate 
• 501441-01-6 5-((5-nitroindol-2-yl)carbonyl)aminoindole-2-carboxylic acid 
• 501441-05-0 1-(1S)-(chloromethyl)-5-hydroxy-3-{5-[(5-nitroindol-2-ylcarbonyl)amino]indole-2-carbonyl}-1,2-dihydro-3H-benz[e]indole 
• 501666-85-9 1-(1S)-(chloromethyl)-5-hydroxy-3-{5-[(5-(3-(acetylthio)propionyl)indol-2-ylcarbonyl)amino]indole-2-carbonyl}-1,2-dihydro-3H-benz[e]indole 
• 17176-77-1 Dibenzyl phosphite 
• 501440-88-6 t-butyl 5-(5-nitroindol-2-ylcarbonylamino)indole-2-carboxylate 
• 501440-90-0 t-butyl 5-(5-aminoindole-2-yl-carbonylamino)indole-2-carboxylate 
• 501440-92-2 t-butyl 5-[5-(3-methyldithiopropionyl)indol-2-yl-carbonylamino]indole-2-carboxylate 
• 501440-94-4 5-[5-(3-(methyldithio)propionyl)indol-2-yl-carbonylamino]indole-2-carboxylic acid 
• 501440-85-3 5-(tert-butyloxycarbonyl)oxy-3-(tert-butyloxycarbonyl)-1-(chloromethyl)-1,2-dihydro-3H-benz[e]indole 
• 615538-51-7 C₃₁H₂₄ClN₅O₃ 
• 501440-84-2 2-[N-(tert-butyloxycarbonyl)((E,Z)-3-chloro-2-propen-1-yl)amino]-4-(tert-butyloxycarbonyl)oxy-1-iodonaphthalene 
• 71086-99-2 ethyl 5-amino-1H-indole-2-carboxylate 
• 16730-20-4 5-nitro-1H-indole-2-carboxylic acid 

Relevant academic research and scientific papers

Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer

The synthesis and biological evaluation of phosphate prodrugs of analogues of 1 (CC-1065) and their conjugates with antibodies are described. The phosphate group on the 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) portion of the compounds conf